DLX4 Antikörper (Middle Region)

Produktnummer ABIN2777375

Produktdetails anti-DLX4 Antikörper

Target: DLX4 (Distal-Less Homeobox 4 (DLX4))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CQQPAALSQP LCGPAEHPQE LEADSEKPRL SPEPSERRPQ APAKKLRKPR

Homologie: Human: 100%, Mouse: 90%, Rat: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against DLX4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DLX4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 240 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DLX4

Target: DLX4 (Distal-Less Homeobox 4 (DLX4))

Andere Bezeichnung: DLX4 (DLX4 Produkte)

Hintergrund: DLX4 may play a role in determining the production of hemoglobin S. May act as a repressor. Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.
Alias Symbols: BP1, DLX7, DLX8, DLX9
Protein Interaction Partner: LSM3, MAGED1,
Protein Size: 240

Molekulargewicht: 26 kDa

Gen-ID: 1748

NCBI Accession: NM_138281, NP_612138

UniProt: Q92988