HDAC6 Antikörper (N-Term)

Produktnummer ABIN2777306

Produktdetails anti-HDAC6 Antikörper

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Rind (Kuh), Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Sequenz: VGLQGMDLNL EAEALAGTGL VLDEQLNEFH CLWDDSFPEG PERLHAIKEQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HDAC6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HDAC6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1215 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HDAC6

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Andere Bezeichnung: HDAC6 (HDAC6 Produkte)

Synonyme: HD6 antikoerper, Hd6 antikoerper, Hdac5 antikoerper, Sfc6 antikoerper, mHDA2 antikoerper, CG6170 antikoerper, DHDAC2 antikoerper, DmHDAC2 antikoerper, Dmel\\CG6170 antikoerper, HDAC antikoerper, HDAC2 antikoerper, dHDAC2 antikoerper, dHDAC6 antikoerper, dmHDA404 antikoerper, hdac6 antikoerper, MGC53140 antikoerper, wu:fc31d02 antikoerper, dsim_GLEANR_17355 antikoerper, DsimGD17207 antikoerper, GD17207 antikoerper, HDAC6 antikoerper, ATHDA6 antikoerper, AXE1 antikoerper, HISTONE DEACETYLASE 6 antikoerper, MDC12.7 antikoerper, MDC12_7 antikoerper, RNA-MEDIATED TRANSCRIPTIONAL SILENCING 1 antikoerper, RPD3B antikoerper, RTS1 antikoerper, SIL1 antikoerper, histone deacetylase 6 antikoerper, histone deacetylase 6 antikoerper, Histone deacetylase 6 antikoerper, histone deacetylase 6 L homeolog antikoerper, GD17207 gene product from transcript GD17207-RB antikoerper, Histone DeAcetylase antikoerper, HDAC6 antikoerper, Hdac6 antikoerper, hdac6.L antikoerper, hdac6 antikoerper, Dsim\HDAC6 antikoerper, PTRG_03035 antikoerper, HDA6 antikoerper, hda-6 antikoerper

Hintergrund: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
Alias Symbols: HD6, JM21
Protein Interaction Partner: HSP90B1, ACTB, UBC, TRIM50, MYH10, DYNC1H1, DDIT3, ELAVL1, MAPK3, MAPK1, RUNX2, TUBA1B, SUMO1, RANBP9, NEDD8, ADRB2, ATXN3, MEF2B, SQSTM1, HSP90AA1, RASSF2, SLMAP, SAV1, CTTNBP2NL, BAG3, SETD8, TUBB, HSPA8, HSPA6, HSPA5, HSPA4, HSPA2, HSPA1L, DNAJA1, ETV6
Protein Size: 1215

Molekulargewicht: 131 kDa, 17 kDa

Gen-ID: 10013

NCBI Accession: NM_006044

UniProt: Q9UBN7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling