HOXB5 Antikörper (N-Term)

Produktnummer ABIN2777303

Produktdetails anti-HOXB5 Antikörper

Target: HOXB5 (Homeobox B5 (HOXB5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXB5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MSSYFVNSFS GRYPNGPDYQ LLNYGSGSSL SGSYRDPAAM HTGSYGYNYN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HOXB5. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 269 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HOXB5 Antikörper (ABIN2777303)

Fu, Lui, Sham, Cheung, Tam: "HOXB5 expression is spatially and temporarily regulated in human embryonic gut during neural crest cell colonization and differentiation of enteric neuroblasts." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 228, Issue 1, pp. 1-10, (2003) (PubMed).

Details zu HOXB5

Target: HOXB5 (Homeobox B5 (HOXB5))

Andere Bezeichnung: HOXB5 (HOXB5 Produkte)

Synonyme: HHO.C10 antikoerper, HOX2 antikoerper, HOX2A antikoerper, HU-1 antikoerper, Hox2.1 antikoerper, AI385717 antikoerper, Hox-2.1 antikoerper, ZF-21 antikoerper, ZF21 antikoerper, hox-2.1 antikoerper, hox-B5 antikoerper, hoxb5 antikoerper, wu:fc38c09 antikoerper, z-18 antikoerper, Ghox-2.1 antikoerper, Hoxb-5 antikoerper, HOXB5 antikoerper, RGD1562292 antikoerper, hox2 antikoerper, hu-1 antikoerper, hox2a antikoerper, hox2.1 antikoerper, hho.c10 antikoerper, XlHbox4 antikoerper, hoxb5-A antikoerper, homeobox B5 antikoerper, homeobox B5a antikoerper, Hox 5 antikoerper, homeo box B5 antikoerper, homeobox B5 S homeolog antikoerper, homeobox protein Hox-B5a antikoerper, HOXB5 antikoerper, Hoxb5 antikoerper, hoxb5a antikoerper, hox5 antikoerper, hoxb5 antikoerper, hoxb5.S antikoerper, LOC101072989 antikoerper

Hintergrund: HOXB5 belongs to the homeobox family. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. The exact role of this gene has yet to be determined.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.
Alias Symbols: HHO.C10, HOX2, HOX2A, HU-1, Hox2.1
Protein Interaction Partner: MAGEA11, CTBP2, CTBP1, TRIM23, UBC,
Protein Size: 269

Molekulargewicht: 30 kDa

Gen-ID: 3215

NCBI Accession: NM_002147, NP_002138

UniProt: P09067