TAL1 Antikörper (N-Term)

Produktnummer ABIN2777291

Produktdetails anti-TAL1 Antikörper

Target: TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TERPPSEAAR SDPQLEGRDA AEASMAPPHL VLLNGVAKET SRAAAAEPPV

Homologie: Cow: 85%, Dog: 85%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 92%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against TAL1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TAL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 331 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TAL1 Antikörper (ABIN2777291)

Hosur, Cox, Burzenski, Riding, Alley, Lyons, Kavirayani, Martin, Cox, Johnson, Shultz: "Retrotransposon insertion in the T-cell acute lymphocytic leukemia 1 (Tal1) gene is associated with severe renal disease and patchy alopecia in Hairpatches (Hpt) mice." in: PLoS ONE, Vol. 8, Issue 1, pp. e53426, (2013) (PubMed).

Details zu TAL1

Target: TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

Andere Bezeichnung: TAL1 (TAL1 Produkte)

Synonyme: SCL/tal-1 antikoerper, Scl antikoerper, bHLHa17 antikoerper, tal-1 antikoerper, SCL antikoerper, TCL5 antikoerper, scl antikoerper, tcl5 antikoerper, SCL-alpha antikoerper, SCL-beta antikoerper, scl/tal1 antikoerper, zgc:85605 antikoerper, T cell acute lymphocytic leukemia 1 antikoerper, TAL bHLH transcription factor 1, erythroid differentiation factor antikoerper, T-cell acute lymphocytic leukemia 1 S homeolog antikoerper, T-cell acute lymphocytic leukemia 1 antikoerper, Tal1 antikoerper, TAL1 antikoerper, tal1.S antikoerper, tal1 antikoerper

Hintergrund: TAL1 is implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. It also serves as a positive regulator of erythroid differentiation
Alias Symbols: SCL, TCL5, tal-1, bHLHa17
Protein Interaction Partner: ELSPBP1, SIN3A, KAT2B, EP300, HOXB9, DRG1, CHD3, ZHX1, STUB1, UBC, RB1, SSBP2, SSBP3, RCOR1, KDM1A, LDB1, TCF12, TCF3, RBBP7, LYL1, HDAC2, HDAC1, CHD4, CBFA2T3, RUNX1, SUPT16H, TAL1, CDK9, TRIM33, SUV39H1, SATB1, TRIM27, NCAPG2, MAPK3, SP1, LMO1, LMO2, GA
Protein Size: 331

Molekulargewicht: 34 kDa

Gen-ID: 6886

NCBI Accession: NM_003189, NP_003180

UniProt: P17542

Pathways: Stem Cell Maintenance