TCEB2 Antikörper (Middle Region)
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- Target Alle TCEB2 Antikörper anzeigen
- TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))
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Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Ziege, Schwein, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TCEB2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- TARPQAPATV GLAFRADDTF EALCIEPFSS PPELPDVMKP QDSGSSANEQ
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TCEB2. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TCEB2
- Top Product
- Discover our top product TCEB2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 118 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))
- Andere Bezeichnung
- TCEB2 (TCEB2 Produkte)
- Synonyme
- 0610040H15Rik antikoerper, cb162 antikoerper, wu:fb47e08 antikoerper, ELOB antikoerper, SIII antikoerper, elongin B antikoerper, Elob antikoerper, elob antikoerper, ELOB antikoerper
- Hintergrund
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TCEB2 is the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: SIII, ELOB
Protein Interaction Partner: vif, TCEB1, SOCS4, CUL5, UBC, PRAME, VHL, ASB18, ASB12, ASB14, ASB15, ASB9, ASB8, ASB7, ASB6, ASB5, ASB10, ASB17, ASB16, ASB13, ASB1, ASB3, LRRC47, LARS, EPRS, CDC42, CUL2, ASB2, Zswim8, CSNK1E, NOS2, NEDD8, HIF1A, CFTR, FEM1B, SOCS3, EPAS1, Lrrc41, Wsb1,
Protein Size: 118 - Molekulargewicht
- 13 kDa
- Gen-ID
- 6923
- NCBI Accession
- NM_007108, NP_009039
- UniProt
- Q15370
- Pathways
- SARS-CoV-2 Protein Interaktom
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