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NFIL3 Antikörper (Middle Region)

NFIL3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777219
  • Target Alle NFIL3 Antikörper anzeigen
    NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
    Bindungsspezifität
    • 11
    • 10
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 43
    • 17
    • 16
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen
    Wirt
    • 41
    • 1
    • 1
    Kaninchen
    Klonalität
    • 43
    Polyklonal
    Konjugat
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NFIL3 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 21
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    GYSHSPPLLQ VNRSSSNSPR TSETDDGVVG KSSDGEDEQQ VPKGPIHSPV
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 85%
    Produktmerkmale
    This is a rabbit polyclonal antibody against NFIL3. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human NFIL3
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 462 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NFIL3 (Nuclear Factor, Interleukin 3 Regulated (NFIL3))
    Andere Bezeichnung
    NFIL3 (NFIL3 Produkte)
    Synonyme
    e4bp4 antikoerper, il3bp1 antikoerper, nfil3a antikoerper, nf-il3a antikoerper, MGC107826 antikoerper, NFIL3 antikoerper, E4BP4 antikoerper, IL3BP1 antikoerper, NF-IL3A antikoerper, NFIL3A antikoerper, E4BP4-1 antikoerper, zgc:100867 antikoerper, AV225605 antikoerper, nuclear factor, interleukin 3 regulated antikoerper, nuclear factor, interleukin 3 regulated L homeolog antikoerper, nuclear factor, interleukin 3, regulated antikoerper, nfil3 antikoerper, NFIL3 antikoerper, Nfil3 antikoerper, nfil3.L antikoerper
    Hintergrund
    NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.
    Alias Symbols: E4BP4, IL3BP1, NF-IL3A, NFIL3A
    Protein Interaction Partner: AMOTL2, TRAF2, MAFF, BATF, NFIL3, MAFG, DDIT3, CBX8, SUMO2, UBC, CREB3, DR1,
    Protein Size: 462
    Molekulargewicht
    51 kDa
    Gen-ID
    4783
    NCBI Accession
    NM_005384, NP_005375
    UniProt
    Q16649
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