Aurora A Antikörper (C-Term)

Produktnummer ABIN2777171

Produktdetails anti-Aurora A Antikörper

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Bindungsspezifität: C-Term

Reaktivität: Human, Rind (Kuh), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aurora A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: ARDLISRLLK HNPSQRPMLR EVLEHPWITA NSSKPSNCQN KESASKQS

Homologie: Cow: 80%, Human: 100%, Sheep: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against AURKA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AURKA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 403 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Andere Bezeichnung: AURKA (AURKA Produkte)

Synonyme: AIK antikoerper, ARK1 antikoerper, AURA antikoerper, AURORA2 antikoerper, BTAK antikoerper, PPP1R47 antikoerper, STK15 antikoerper, STK6 antikoerper, STK7 antikoerper, AIRK1 antikoerper, AU019385 antikoerper, AW539821 antikoerper, Ark1 antikoerper, Aurora-A antikoerper, Ayk1 antikoerper, IAK antikoerper, IAK1 antikoerper, Stk6 antikoerper, 87A7-9/2 antikoerper, Aur-A antikoerper, AurA antikoerper, CG3068 antikoerper, Dmel\\CG3068 antikoerper, aur-A antikoerper, aurA antikoerper, ck10 antikoerper, ck[10] antikoerper, l(3)87Ac antikoerper, l(3)ck10 antikoerper, ARK-1 antikoerper, Eg2 antikoerper, aik antikoerper, ark1 antikoerper, aur-a antikoerper, aura antikoerper, aurka-a antikoerper, aurora2 antikoerper, btak antikoerper, stk15 antikoerper, stk6 antikoerper, stk7 antikoerper, pEg2 antikoerper, wu:fb37c10 antikoerper, wu:fc02c02 antikoerper, zgc:100912 antikoerper, AURKA antikoerper, aurka antikoerper, aurora kinase A antikoerper, aurora A antikoerper, aurora kinase A L homeolog antikoerper, hypothetical protein antikoerper, aurora kinase A S homeolog antikoerper, AURKA antikoerper, Aurka antikoerper, aurA antikoerper, aurka.L antikoerper, aurka antikoerper, Aurora-A antikoerper, aurka.S antikoerper

Hintergrund: AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
Alias Symbols: AIK, ARK1, AURA, AURORA2, BTAK, MGC34538, STK15, STK6, STK7, PPP1R47
Protein Interaction Partner: CHFR, GADD45A, RPLP2, RPLP0, RPL38, RPL30, RPL27, RPL22, RPL12, RPL11, PSMB7, PSMB5, PSMA6, PSMA5, PSMA1, MAPK6, PPP6C, PCMT1, YBX1, NPM1, NCL, MFAP4, LYZ, ILF3, ILF2, IARS, HSPD1, HSP90AB1, HSP90AA1, HSPA9, HSPA8, HSPA5, HSPA2, HSPA1A, HNRNPU, HNRNPA2B1,
Protein Size: 403

Molekulargewicht: 46 kDa

Gen-ID: 6790

NCBI Accession: NM_003600, NP_003591

UniProt: O14965

Pathways: Zellzyklus, Asymmetric Protein Localization