Stanniocalcin 1 Antikörper (N-Term)

Produktnummer ABIN2777144

Produktdetails anti-Stanniocalcin 1 Antikörper

Target: Stanniocalcin 1 (STC1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Hund, Schwein, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Stanniocalcin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MLQNSAVLLV LVISASATHE AEQNDSVSPR KSRVAAQNSA EVVRCLNSAL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against STC1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 247 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Stanniocalcin 1 Antikörper (ABIN2777144)

Gao, Xu, Chen, Wang, Wang, Wu, Yuan: "Potential protein toxicity of synthetic pigments: binding of poncean S to human serum albumin." in: Biophysical journal, Vol. 94, Issue 3, pp. 906-17, (2008) (PubMed).

Details zu Stanniocalcin 1

Target: Stanniocalcin 1 (STC1)

Andere Bezeichnung: STC1 (STC1 Produkte)

Synonyme: STC antikoerper, Stc antikoerper, stc1 antikoerper, MGC82280 antikoerper, STC1 antikoerper, zgc:153307 antikoerper, LOC777959 antikoerper, stanniocalcin 1 antikoerper, stanniocalcin 1 L homeolog antikoerper, stanniocalcin 1 S homeolog antikoerper, STC1 antikoerper, Stc1 antikoerper, stc1.L antikoerper, stc1.S antikoerper, stc1 antikoerper, LOC777959 antikoerper

Hintergrund: STC1 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. It contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate.This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: STC
Protein Size: 247

Molekulargewicht: 26 kDa

Gen-ID: 6781

NCBI Accession: NM_003155, NP_003146

UniProt: P52823

Pathways: Hormone Activity