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APCS Antikörper (N-Term)

APCS Reaktivität: Human, Maus, Ratte, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777091
  • Target Alle APCS Antikörper anzeigen
    APCS (Amyloid P Component, Serum (APCS))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 65
    • 13
    • 9
    • 1
    • 1
    Human, Maus, Ratte, Meerschweinchen
    Wirt
    • 61
    • 15
    • 3
    Kaninchen
    Klonalität
    • 65
    • 14
    Polyklonal
    Konjugat
    • 45
    • 9
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser APCS Antikörper ist unkonjugiert
    Applikation
    • 52
    • 38
    • 37
    • 9
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    NFTLCFRAYS DLSRAYSLFS YNTQGRDNEL LVYKERVGEY SLYIGRHKVT
    Homologie
    Guinea Pig: 86%, Human: 100%, Mouse: 77%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against APCS. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human APCS
    Top Product
    Discover our top product APCS Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 223 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Veerhuis, Boshuizen, Morbin, Mazzoleni, Hoozemans, Langedijk, Tagliavini, Langeveld, Eikelenboom: "Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q." in: Neurobiology of disease, Vol. 19, Issue 1-2, pp. 273-82, (2005) (PubMed).

  • Target
    APCS (Amyloid P Component, Serum (APCS))
    Andere Bezeichnung
    APCS (APCS Produkte)
    Synonyme
    PTX2 antikoerper, SAP antikoerper, Sap antikoerper, APCS antikoerper, FP antikoerper, SAP(FP) antikoerper, apcs antikoerper, ptx2 antikoerper, sap antikoerper, amyloid P component, serum antikoerper, serum amyloid P-component antikoerper, amyloid P component, serum protein L homeolog antikoerper, APCS antikoerper, Apcs antikoerper, apcs.L antikoerper
    Hintergrund
    APCS is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. This gene has multiple polyadenylation sites.
    Alias Symbols: MGC88159, PTX2, SAP
    Protein Interaction Partner: COPS5, GK, HES1, GRB2, GOT2, FCGR3B, FCGR2B, CALU, TG, LAMA1, FCGR1A, FCGR3A, FN1, CRP, C4BPA, C1QA, COL4A1, APCS,
    Protein Size: 223
    Molekulargewicht
    25 kDa
    Gen-ID
    325
    NCBI Accession
    NM_001639, NP_001630
    UniProt
    P02743
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