HSD3B1 Antikörper (N-Term)

Produktnummer ABIN2777011

Produktdetails anti-HSD3B1 Antikörper

Target: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Schwein, Schaf, Rind (Kuh), Ziege, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD3B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TGWSCLVTGA GGFLGQRIIR LLVKEKELKE IRVLDKAFGP ELREEFSKLQ

Homologie: Cow: 79%, Goat: 82%, Horse: 79%, Human: 100%, Pig: 79%, Rat: 79%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against HSD3B1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HSD3B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 373 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HSD3B1 Antikörper (ABIN2777011)

Mirkheshti, Park, Jiang, Cropper, Werner, Song, Chatterjee: "Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer." in: Oncotarget, Vol. 7, Issue 38, pp. 62240-62254, (2016) (PubMed).

Details zu HSD3B1

Target: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Andere Bezeichnung: HSD3B1 (HSD3B1 Produkte)

Synonyme: 3BETAHSD antikoerper, HSD3B antikoerper, HSDB3 antikoerper, HSDB3A antikoerper, I antikoerper, SDR11E1 antikoerper, HSD3B1 antikoerper, MGC131206 antikoerper, D3Ertd383e antikoerper, 3B-HSD antikoerper, 3BHSD antikoerper, si:rp71-68n21.10 antikoerper, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 antikoerper, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 antikoerper, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 L homeolog antikoerper, HSD3B1 antikoerper, LOC469446 antikoerper, LOC713091 antikoerper, hsd3b1.L antikoerper, LOC100451655 antikoerper, Hsd3b1 antikoerper, hsd3b1 antikoerper

Hintergrund: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
Alias Symbols: HSD3B, HSDB3, I, HSDB3A, SDR11E1, 3BETAHSD
Protein Size: 373

Molekulargewicht: 42 kDa

Gen-ID: 3283

NCBI Accession: NM_000862, NP_000853

UniProt: P14060

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis