GHRHR Antikörper (N-Term)

Produktnummer ABIN2777008

Produktdetails anti-GHRHR Antikörper

Target: GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Schwein, Rind (Kuh), Schaf, Hund, Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GHRHR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VTLPCPDFFS HFSSESGAVK RDCTITGWSE PFPPYPVACP VPLELLAEEE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 85%, Horse: 77%, Human: 100%, Pig: 86%, Rabbit: 79%, Rat: 93%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against GHRHR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GHRHR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 423 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GHRHR

Target: GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))

Andere Bezeichnung: GHRHR (GHRHR Produkte)

Synonyme: GHRFR antikoerper, GRFR antikoerper, IGHD1B antikoerper, Ghrfr antikoerper, lit antikoerper, little antikoerper, GHRHREC antikoerper, GHRH-R antikoerper, growth hormone releasing hormone receptor antikoerper, GHRHR antikoerper, Ghrhr antikoerper

Hintergrund: GHRHR is a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in its gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.This This gene, expressed in the pituitary, encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. Many alternate transcriptional splice variants encoding different isoforms have been described, but only two have been characterized to date.
Alias Symbols: GHRFR, GHRHRpsv, GRFR, IGHD1B
Protein Interaction Partner: GHRH, GHRL, MLNR,
Protein Size: 423

Molekulargewicht: 47 kDa

Gen-ID: 2692

NCBI Accession: NM_000823, NP_000814

UniProt: Q02643

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Hormone Transport, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process