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ALAS2 Antikörper (C-Term)

ALAS2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Ziege, Schaf WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2776924
  • Target Alle ALAS2 Antikörper anzeigen
    ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))
    Bindungsspezifität
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 46
    • 35
    • 31
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Ziege, Schaf
    Wirt
    • 37
    • 9
    Kaninchen
    Klonalität
    • 36
    • 10
    Polyklonal
    Konjugat
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ALAS2 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 13
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    PTVPRGEELL RLAPSPHHSP QMMEDFVEKL LLAWTAVGLP LQDVSVAACN
    Homologie
    Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 79%, Zebrafish: 85%
    Produktmerkmale
    This is a rabbit polyclonal antibody against ALAS2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human ALAS2
    Top Product
    Discover our top product ALAS2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 550 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Chien, Chang, Lee, Su, Wu: "Non-genomic immunosuppressive actions of progesterone inhibits PHA-induced alkalinization and activation in T cells." in: Journal of cellular biochemistry, Vol. 99, Issue 1, pp. 292-304, (2006) (PubMed).

  • Target
    ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))
    Andere Bezeichnung
    ALAS2 (ALAS2 Produkte)
    Synonyme
    anh1 antikoerper, asb antikoerper, xlsa antikoerper, ALAS-E antikoerper, ALASE antikoerper, ANH1 antikoerper, ASB antikoerper, XLDPP antikoerper, XLEPP antikoerper, XLSA antikoerper, alas-e antikoerper, cb1063 antikoerper, sau antikoerper, sauternes antikoerper, ALAS antikoerper, Alas-2 antikoerper, 5'-aminolevulinate synthase 2 antikoerper, aminolevulinate, delta-, synthase 2 antikoerper, aminolevulinic acid synthase 2, erythroid antikoerper, alas2 antikoerper, ALAS2 antikoerper, Alas2 antikoerper, alas2.L antikoerper
    Hintergrund
    ALAS2 specifies an erythroid-specific mitochondrially located enzyme. The protein catalyzes the first step in the heme biosynthetic pathway. Defects in its gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Alias Symbols: ANH1, ASB, XLSA, ALASE, XLDPP, XLEPP, ALAS-E
    Protein Interaction Partner: BANP, GRB2, SUCLA2, RABGGTB,
    Protein Size: 550
    Molekulargewicht
    60 kDa
    Gen-ID
    212
    NCBI Accession
    NM_001037967, NP_001033056
    UniProt
    P22557
    Pathways
    Transition Metal Ion Homeostasis
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