DDC Antikörper (N-Term)

Produktnummer ABIN2776802

Produktdetails anti-DDC Antikörper

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: EFRRRGKEMV DYVANYMEGI EGRQVYPDVE PGYLRPLIPA AAPQEPDTFE

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 92%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against DDC. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDC

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 480 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-DDC Antikörper (ABIN2776802)

Shimohata, Ishihara, Hattori, Miyamoto, Morishita, Ornthanalai, Raveau, Ebrahim, Amano, Yamada, Sago, Akiba, Mataga, Murphy, Miyakawa, Yamakawa: "Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism." in: Experimental neurology, Vol. 293, pp. 1-12, (2017) (PubMed).

Details zu DDC

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Andere Bezeichnung: DDC (DDC Produkte)

Synonyme: AADC antikoerper, wu:fa56d05 antikoerper, wu:fd59h03 antikoerper, wu:fk20h01 antikoerper, zgc:65801 antikoerper, zgc:76929 antikoerper, Ddc antikoerper, DdcDv antikoerper, Dvir\\GJ17995 antikoerper, GJ17995 antikoerper, dvir_GLEANR_2561 antikoerper, Aadc antikoerper, 5-HT antikoerper, CG10697 antikoerper, DDC antikoerper, DdcDm antikoerper, Dmel\\CG10697 antikoerper, ddc antikoerper, fDDC antikoerper, l(2)37Bl antikoerper, l(2)37Ch antikoerper, l(2)k02104 antikoerper, dopa decarboxylase antikoerper, Dopa-decarboxylase antikoerper, dopa decarboxylase (aromatic L-amino acid decarboxylase) antikoerper, Dopa decarboxylase antikoerper, dopa decarboxylase L homeolog antikoerper, DDC antikoerper, ddc antikoerper, Ddc antikoerper, Dvir\Ddc antikoerper, ddc.L antikoerper

Hintergrund: DDC catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
Alias Symbols: AADC
Protein Interaction Partner: ATF6, RELA, AR,
Protein Size: 480

Molekulargewicht: 53 kDa

Gen-ID: 1644

NCBI Accession: NM_000790, NP_000781

UniProt: P20711

Pathways: Dopaminergic Neurogenesis