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CDC25B Antikörper (N-Term)

CDC25B Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2776752
  • Target Alle CDC25B Antikörper anzeigen
    CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
    Bindungsspezifität
    • 27
    • 22
    • 18
    • 15
    • 15
    • 10
    • 9
    • 9
    • 8
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 136
    • 104
    • 54
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen
    Wirt
    • 184
    • 2
    Kaninchen
    Klonalität
    • 175
    • 11
    Polyklonal
    Konjugat
    • 71
    • 15
    • 12
    • 11
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    Dieser CDC25B Antikörper ist unkonjugiert
    Applikation
    • 166
    • 79
    • 52
    • 52
    • 35
    • 30
    • 14
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    TQTMHDLAGL GSETPKSQVG TLLFRSRSRL THLSLSRRAS ESSLSSESSE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CDC25B. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CDC25B
    Top Product
    Discover our top product CDC25B Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 580 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))
    Andere Bezeichnung
    CDC25B (CDC25B Produkte)
    Synonyme
    CDC25B antikoerper, AI604853 antikoerper, cell division cycle 25B antikoerper, cdc25b antikoerper, CDC25B antikoerper, Cdc25b antikoerper
    Hintergrund
    CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined.CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
    Protein Interaction Partner: BTRC, UBC, FBXW11, MAPK9, CDK5, CDK1, YWHAQ, MAPKAPK2, UBD, BRSK2, CDC14A, CDK2, Cdc25b, FOXM1, BRSK1, FHL3, KAT2B, MELK, YWHAE, CHEK1, AURKA, SFN, YWHAB, YWHAZ, MAPK14, CREBBP, AR, ESR1, CSNK2B, CSNK2A1, YWHAH, PGR, PHB2, KRT85, KRT35, KRT31,
    Protein Size: 580
    Molekulargewicht
    65 kDa
    Gen-ID
    994
    NCBI Accession
    NM_021873, NP_068659
    UniProt
    P30305
    Pathways
    Zellzyklus, M Phase, Autophagie
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