ILF2 Antikörper (C-Term)

Produktnummer ABIN2776419

Produktdetails anti-ILF2 Antikörper

Target: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ILF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: HGGFRKILGQ EGDASYLASE ISTWDGVIVT PSEKAYEKPP EKKEGEEEEE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ILF2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ILF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 390 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ILF2 Antikörper (ABIN2776419)

Yamauchi, Nakamura, Hiramoto, Yuri, Yokota, Naitou, Takeuchi, Yamanaka, Kita, Nakahara, Kinoyama, Matsuhisa, Kaneko, Koutoku, Sasamata, Kobori, Katou, Tawara, Kawabata, Furuichi: "Sepantronium bromide (YM155) induces disruption of the ILF3/p54(nrb) complex, which is required for survivin expression." in: Biochemical and biophysical research communications, Vol. 425, Issue 4, pp. 711-6, (2012) (PubMed).

Jiang, Zhou, Moxley, Jarrett: "Purification and identification of positive regulators binding to a novel element in the c-Jun promoter." in: Biochemistry, Vol. 47, Issue 35, pp. 9318-34, (2008) (PubMed).

Details zu ILF2

Target: ILF2 (Interleukin Enhancer Binding Factor 2, 45kDa (ILF2))

Andere Bezeichnung: ILF2 (ILF2 Produkte)

Synonyme: nf45 antikoerper, pro3063 antikoerper, ILF2 antikoerper, wu:fb34h01 antikoerper, zgc:73084 antikoerper, zgc:77276 antikoerper, NF45 antikoerper, PRO3063 antikoerper, 6230405A16Rik antikoerper, TEG-267 antikoerper, Tex261 antikoerper, Tex267 antikoerper, interleukin enhancer binding factor 2 antikoerper, interleukin enhancer binding factor 2 L homeolog antikoerper, ilf2 antikoerper, ILF2 antikoerper, ilf2.L antikoerper, Ilf2 antikoerper

Hintergrund: Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of which is the product of the ILF2 gene. The encoded protein binds strongly to the 90 kDa protein and stimulates its ability to enhance gene expression.
Alias Symbols: NF45, PRO3063
Protein Interaction Partner: CCNDBP1, HUWE1, UBC, EEF1G, AURKA, SUMO2, SUMO3, STAU1, IVNS1ABP, RPA1, SMURF2, RPA3, RPA2, ERG, EZH2, BMI1, SUZ12, EED, rev, HNRNPU, FKBP3, DHX9, DDX1, ABCF1, C14orf166, RTCB, DIMT1, NELFB, EDC4, IGF2BP3, EIF2B2, EIF2B3, YBX3, RFC4, PTBP1, YBX1, NMT1, MR
Protein Size: 390

Molekulargewicht: 43 kDa

Gen-ID: 3608

NCBI Accession: NM_004515, NP_004506

UniProt: Q12905