GABRG2 Antikörper (C-Term)

Produktnummer ABIN2776351

Produktdetails anti-GABRG2 Antikörper

Target: GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABRG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AMDLFVSVCF IFVFSALVEY GTLHYFVSNR KPSKDKDKKK KNPAPTIDIR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GABRG2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GABRG2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 327 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GABRG2

Target: GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))

Andere Bezeichnung: GABRG2 (GABRG2 Produkte)

Synonyme: cae2 antikoerper, eca2 antikoerper, gabrg1 antikoerper, gefsp3 antikoerper, si:ch211-145n14.1 antikoerper, CAE2 antikoerper, ECA2 antikoerper, GEFSP3 antikoerper, GABAA-R antikoerper, Gabrg-2 antikoerper, gamma2 antikoerper, gamma-aminobutyric acid type A receptor gamma2 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, gamma 2 antikoerper, gamma-aminobutyric acid type A receptor gamma 2 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 antikoerper, GABRG2 antikoerper, gabrg2 antikoerper, Gabrg2 antikoerper

Hintergrund: Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits. GABRG2 is the gamma 2 subunit of GABA(A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures.Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits. This gene encodes the gamma 2 subunit of GABA(A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures. Alternative splicing of this gene results in transcript variants encoding different isoforms.
Alias Symbols: CAE2, ECA2, GEFSP3
Protein Interaction Partner: ZDHHC3, GABARAP, PRKCB, PRKCA, GABRG2, DRD5, PPP3CA,
Protein Size: 327

Molekulargewicht: 36 kDa

Gen-ID: 2566

NCBI Accession: NM_198903, NP_944493

UniProt: P18507