KCND3 Antikörper (Middle Region)

Produktnummer ABIN2776308

Produktdetails anti-KCND3 Antikörper

Target: KCND3 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCND3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VAKTGSSNAY LHSKRNGLLN EALELTGTPE EEHMGKTTSL IESQHHHLLH

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KCND3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KCND3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 636 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KCND3

Target: KCND3 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3))

Andere Bezeichnung: KCND3 (KCND3 Produkte)

Synonyme: KCND3 antikoerper, zgc:55306 antikoerper, wu:fi06g01 antikoerper, kv4.3 antikoerper, K(v)4.3 antikoerper, AW045978 antikoerper, Kncd3 antikoerper, Kv4.3 antikoerper, KCND3L antikoerper, KCND3S antikoerper, KSHIVB antikoerper, KV4.3 antikoerper, kcnd3-A antikoerper, xKv4.3 antikoerper, potassium voltage-gated channel subfamily D member 3 antikoerper, potassium voltage-gated channel, Shal-related subfamily, member 3 antikoerper, potassium channel, voltage gated Shal related subfamily D, member 3 antikoerper, potassium voltage-gated channel, Shal-related family, member 3 antikoerper, potassium channel, voltage gated Shal related subfamily D, member 3 L homeolog antikoerper, KCND3 antikoerper, kcnd3 antikoerper, Kcnd3 antikoerper, kcnd3.L antikoerper

Hintergrund: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). KCND3 encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.
Alias Symbols: KCND3L, KCND3S, KSHIVB, KV4.3, MGC142035, MGC142037
Protein Interaction Partner: NDUFS2, NAP1L1, LBR, HSPA8, HSPA5, HNRNPF, XRCC6, EWSR1, EMD, DDB1, CUX1, CDK1, AUP1, NONO, XRCC5, UQCRC2, TUBB2A, RCN2, Rapgef5, Rapgef4, Kcnip1, Rapgef3, Kcnip2, DPP10, PYCR2, VPS4A, TUBA1B, G3BP1, RUVBL1, CNBP, SRC, KCND3,
Protein Size: 636

Molekulargewicht: 71 kDa

Gen-ID: 3752

NCBI Accession: NM_172198, NP_751948

UniProt: Q14D71