KCNMB3 Antikörper (Middle Region)

Produktnummer ABIN2776296

Produktdetails anti-KCNMB3 Antikörper

Target: KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNMB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SLTLLGGALI VGMVRLTQHL SLLCEKYSTV VRDEVGGKVP YIEQHQFKLC

Homologie: Dog: 91%, Human: 100%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against KCNMB3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KCNMB3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 277 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KCNMB3

Target: KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))

Andere Bezeichnung: KCNMB3 (KCNMB3 Produkte)

Synonyme: KCNMB3 antikoerper, BKBETA3 antikoerper, HBETA3 antikoerper, KCNMB2 antikoerper, KCNMBL antikoerper, SLOBETA3 antikoerper, EG435726 antikoerper, Gm5707 antikoerper, potassium calcium-activated channel subfamily M regulatory beta subunit 3 antikoerper, potassium channel subfamily M regulatory beta subunit 3 S homeolog antikoerper, potassium large conductance calcium-activated channel, subfamily M beta member 3 antikoerper, potassium large conductance calcium-activated channel, subfamily M, beta member 3 antikoerper, KCNMB3 antikoerper, kcnmb3.S antikoerper, Kcnmb3 antikoerper

Hintergrund: KCNMB3 is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for KCNMB3.MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. At least four transcript variants encoding four different isoforms have been found for this gene.
Alias Symbols: KCNMB2, KCNMBL, HBETA3, BKBETA3, SLOBETA3
Protein Size: 277

Molekulargewicht: 31 kDa

Gen-ID: 27094

NCBI Accession: NM_171828, NP_741979