GABRB3 Antikörper (Middle Region)
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- Target Alle GABRB3 Antikörper anzeigen
- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GABRB3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- ESYGYTTDDI EFYWRGGDKA VTGVERIELP QFSIVEHRLV SRNVVFATGA
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against GABRB3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GABRB3
- Top Product
- Discover our top product GABRB3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 473 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
- Andere Bezeichnung
- GABRB3 (GABRB3 Produkte)
- Synonyme
- GABRB3 antikoerper, eca5 antikoerper, LOC100230475 antikoerper, ECA5 antikoerper, A230092K12Rik antikoerper, AW049585 antikoerper, Cp1 antikoerper, Gabrb-3 antikoerper, beta3 antikoerper, gamma-aminobutyric acid type A receptor beta3 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, beta 3 antikoerper, gamma-aminobutyric acid type A receptor beta 3 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 antikoerper, GABRB3 antikoerper, gabrb3 antikoerper, Gabrb3 antikoerper
- Hintergrund
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GABRB3 is a member of the ligand-gated ionic channel family. GABRB3 is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism.This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding isoforms with distinct signal peptides have been described.
Alias Symbols: MGC9051, ECA5
Protein Interaction Partner: MEOX2, UBC, UBQLN1, ARFGEF2, PPP2CA, AKAP5, GNB2L1, PRKCA, PRKACA,
Protein Size: 473 - Molekulargewicht
- 52 kDa
- Gen-ID
- 2562
- NCBI Accession
- NM_021912, NP_068712
- UniProt
- P28472
- Pathways
- Sensory Perception of Sound
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