TNFAIP1 Antikörper (C-Term)

Produktnummer ABIN2776237

Produktdetails anti-TNFAIP1 Antikörper

Target: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Hund, Meerschweinchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFAIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LNVLLYETPR VPDNSLLEAT SRSRSQASPS EDEDTFELRD RVRRIHVKRY

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Tnfaip1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of RAT Tnfaip1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNFAIP1

Target: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Andere Bezeichnung: Tnfaip1 (TNFAIP1 Produkte)

Synonyme: zgc:55302 antikoerper, wu:fi06b02 antikoerper, TNFAIP1 antikoerper, B12 antikoerper, B61 antikoerper, BTBD34 antikoerper, EDP1 antikoerper, hBACURD2 antikoerper, Edp-1 antikoerper, Edp1 antikoerper, Tnfip1 antikoerper, tumor necrosis factor, alpha-induced protein 1 (endothelial) antikoerper, TNF alpha induced protein 1 antikoerper, TNF alpha induced protein 1 L homeolog antikoerper, tnfaip1 antikoerper, TNFAIP1 antikoerper, Tnfaip1 antikoerper, tnfaip1.L antikoerper

Hintergrund: Tnfaip1 is a substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis.
Alias Symbols: Edp1
Protein Interaction Partner: Pcna,
Protein Size: 316

Molekulargewicht: 34 kDa

Gen-ID: 287543

NCBI Accession: NM_182950, NP_891995

UniProt: Q7TNY1