TRPC6 Antikörper (Middle Region)

Produktnummer ABIN2776163

Produktdetails anti-TRPC6 Antikörper

Target: TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Schwein, Pferd, Rind (Kuh), Hund, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KKGFQEDAEM NKINEEKKLG ILGSHEDLSK LSLDKKQVGH NKQPSIRSSE

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 77%, Yeast: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TRPC6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRPC6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 931 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRPC6

Target: TRPC6 (Transient Receptor Potential Cation Channel, Subfamily C, Member 6 (TRPC6))

Andere Bezeichnung: TRPC6 (TRPC6 Produkte)

Synonyme: FSGS2 antikoerper, TRP6 antikoerper, AV025995 antikoerper, LLHWJM002 antikoerper, LLHWJM003 antikoerper, LLHWJM004 antikoerper, TRP-6 antikoerper, Trrp6 antikoerper, mtrp6 antikoerper, trp6 antikoerper, bZ1P14.9 antikoerper, si:rp71-1p14.9 antikoerper, trpc6 antikoerper, transient receptor potential cation channel subfamily C member 6 antikoerper, transient receptor potential cation channel, subfamily C, member 6 antikoerper, transient receptor potential cation channel, subfamily C, member 6a antikoerper, TRPC6 antikoerper, Trpc6 antikoerper, trpc6a antikoerper, trpc6 antikoerper

Hintergrund: TRPC6 forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Alias Symbols: FLJ11098, FLJ14863, FSGS2, TRP6
Protein Interaction Partner: RNF24, TRPC3, ORAI1, TRPM2, TRPC6, SRC, ITPR3, MX1, FYN, TRPC7, TRPC5, TRPC4, TRPC1, TRPC2, ITPR1,
Protein Size: 931

Molekulargewicht: 106 kDa

Gen-ID: 7225

NCBI Accession: NM_004621, NP_004612

UniProt: Q9Y210