Glutamate Receptor 3 Antikörper (Middle Region)

Produktnummer ABIN2776119

Produktdetails anti-Glutamate Receptor 3 Antikörper

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutamate Receptor 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TVERMVSPIE SAEDLAKQTE IAYGTLDSGS TKEFFRRSKI AVYEKMWSYM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Gria3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Rat Gria3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 888 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Andere Bezeichnung: Gria3 (GRIA3 Produkte)

Synonyme: AMPA antikoerper, gria3 antikoerper, GRIN3A antikoerper, glur3b antikoerper, gria3.2 antikoerper, zfGRIA3[b] antikoerper, si:bz1o18.1 antikoerper, SI:zC231H1.1 antikoerper, si:zc140k5.3 antikoerper, GLUR3 antikoerper, GLUR-C antikoerper, GLUR3/C antikoerper, GRIA3 antikoerper, glur3 antikoerper, GluA3 antikoerper, GluR-3 antikoerper, GluR-C antikoerper, GluR-K3 antikoerper, GLUR-K3 antikoerper, GLURC antikoerper, MRX94 antikoerper, 2900064I19Rik antikoerper, Glur-3 antikoerper, Glur3 antikoerper, Gluralpha3 antikoerper, glutamate receptor, ionotropic, AMPA 3b antikoerper, glutamate ionotropic receptor AMPA type subunit 3 antikoerper, glutamate receptor, ionotropic, AMPA 3 antikoerper, glutamate receptor, ionotropic, AMPA 3 L homeolog antikoerper, glutamate receptor, ionotropic, AMPA3 (alpha 3) antikoerper, gria3b antikoerper, GRIA3 antikoerper, gria3 antikoerper, gria3.L antikoerper, Gria3 antikoerper

Hintergrund: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
Alias Symbols: GLUR3, GluA3|GluR-3|GluR-C|GluR-K3
Protein Interaction Partner: Ubc, Sdcbp, Grip1, Pick1,
Protein Size: 888

Molekulargewicht: 97 kDa

Gen-ID: 29628

NCBI Accession: NM_032990, NP_116785

UniProt: P19492

Pathways: PI3K-Akt Signalweg, cAMP Metabolic Process, Synaptic Membrane