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CHRNA4 Antikörper (N-Term)

CHRNA4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Hund, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2776101
  • Target Alle CHRNA4 Antikörper anzeigen
    CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
    Bindungsspezifität
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Hund, Pferd, Zebrafisch (Danio rerio)
    Wirt
    • 22
    • 5
    • 1
    Kaninchen
    Klonalität
    • 24
    • 4
    Polyklonal
    Konjugat
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CHRNA4 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    AEERLLKKLF SGYNKWSRPV ANISDVVLVR FGLSIAQLID VDEKNQMMTT
    Homologie
    Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CHRNA4. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CHRNA4
    Top Product
    Discover our top product CHRNA4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 627 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ishizuka, Ozawa, Goshima, Watanabe: "Involvement of nicotinic acetylcholine receptor in the proliferation of mouse induced pluripotent stem cells." in: Life sciences, Vol. 90, Issue 17-18, pp. 637-48, (2012) (PubMed).

  • Target
    CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))
    Andere Bezeichnung
    CHRNA4 (CHRNA4 Produkte)
    Synonyme
    NACHRA4 antikoerper, BFNC antikoerper, EBN antikoerper, EBN1 antikoerper, NACHR antikoerper, NACRA4 antikoerper, NARAC antikoerper, Acra-4 antikoerper, Acra4 antikoerper, ENFL1 antikoerper, neuronal acetylcholine receptor subunit alpha-4 antikoerper, neuronal acetylcholine receptor subunit alpha-4-like antikoerper, cholinergic receptor nicotinic alpha 4 subunit antikoerper, cholinergic receptor, nicotinic, alpha 4b antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 4 antikoerper, CpipJ_CPIJ002434 antikoerper, LOC100368057 antikoerper, CHRNA4 antikoerper, chrna4b antikoerper, Chrna4 antikoerper
    Hintergrund
    CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: BFNC, EBN, EBN1, NACRA4, NACHR, NACHRA4
    Protein Interaction Partner: Ubqln1, CSNK2B, VSNL1, CHRNB4, CHRNB2, YWHAH, CRELD2,
    Protein Size: 627
    Molekulargewicht
    67 kDa
    Gen-ID
    1137
    NCBI Accession
    NM_000744, NP_000735
    UniProt
    P43681
    Pathways
    Synaptic Membrane
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