CACNA2D1 Antikörper (Middle Region)

Produktnummer ABIN2776091

Produktdetails anti-CACNA2D1 Antikörper

Target: CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA2D1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PKSQEPVTLD FLDAELENDI KVEIRNKMID GESGEKTFRT LVKSQDERYI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CACNA2D1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CACNA2D1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1091 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CACNA2D1 Antikörper (ABIN2776091)

Tétreault, Bourdin, Briot, Segura, Lesage, Fiset, Parent: "Identification of Glycosylation Sites Essential for Surface Expression of the CaVα2δ1 Subunit and Modulation of the Cardiac CaV1.2 Channel Activity." in: The Journal of biological chemistry, Vol. 291, Issue 9, pp. 4826-43, (2016) (PubMed).

Stotz, Barr, McRory, Chen, Jarvis, Zamponi: "Several structural domains contribute to the regulation of N-type calcium channel inactivation by the beta 3 subunit." in: The Journal of biological chemistry, Vol. 279, Issue 5, pp. 3793-800, (2004) (PubMed).

Details zu CACNA2D1

Target: CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))

Andere Bezeichnung: CACNA2D1 (CACNA2D1 Produkte)

Synonyme: CACNA2D1 antikoerper, DKFZp469K2211 antikoerper, CACNA2 antikoerper, CACNL2A antikoerper, CCHL2A antikoerper, Ca(v)alpha2delta1 antikoerper, Cacna2 antikoerper, Cchl2a antikoerper, CCHLA2 antikoerper, DHSCCA antikoerper, calcium voltage-gated channel auxiliary subunit alpha2delta 1 antikoerper, calcium channel, voltage-dependent, alpha 2/delta subunit 1 antikoerper, calcium channel, voltage-dependent, alpha2/delta subunit 1 antikoerper, CACNA2D1 antikoerper, cacna2d1 antikoerper, Cacna2d1 antikoerper

Hintergrund: CACNA2D1 encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
Alias Symbols: CACNA2, CCHL2A, CACNL2A
Protein Interaction Partner: STT3B, RAB11A, NDUFS4, Cep76,
Protein Size: 1091

Molekulargewicht: 120 kDa

Gen-ID: 781

NCBI Accession: NM_000722, NP_000713

UniProt: P54289