SCNN1B Antikörper (C-Term)

Produktnummer ABIN2776090

Produktdetails anti-SCNN1B Antikörper

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Meerschweinchen, Ziege, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCNN1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QPDTAPRSPN TGPYPSEQAL PIPGTPPPNY DSLRLQPLDV IESDSEGDAI

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SCNN1B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SCNN1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 640 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SCNN1B

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Andere Bezeichnung: SCNN1B (SCNN1B Produkte)

Synonyme: BESC1 antikoerper, ENaCb antikoerper, ENaCbeta antikoerper, SCNEB antikoerper, RNENACB antikoerper, besc1 antikoerper, betaxENaC antikoerper, enacb antikoerper, enacbeta antikoerper, scnn1b antikoerper, beta-ENaC antikoerper, scneb antikoerper, SCNN1B antikoerper, BETA-ENAC antikoerper, sodium channel epithelial 1 beta subunit antikoerper, sodium channel, non voltage gated 1 beta subunit L homeolog antikoerper, sodium channel, non voltage gated 1 beta subunit antikoerper, sodium channel, nonvoltage-gated 1 beta antikoerper, sodium channel, non voltage gated 1 beta subunit S homeolog antikoerper, SCNN1B antikoerper, Scnn1b antikoerper, scnn1b.L antikoerper, scnn1b antikoerper, scnn1b.S antikoerper

Hintergrund: When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.
Alias Symbols: BESC1, ENaCb, SCNEB, ENaCbeta
Protein Interaction Partner: NEDD4L, SERP1, SCNN1G, SCNN1A, COMMD1, UBC, USP2, RAF1, NEDD4, TSC22D3, SGK1, EPN1, AP1M2, NFASC, CNTN1, WWP2, SCNN1D, ANK3, STX1A, ITCH, HECW1,
Protein Size: 640

Molekulargewicht: 70 kDa

Gen-ID: 6338

NCBI Accession: NM_000336, NP_000327

UniProt: P51168