LIMA1 Antikörper (Middle Region)

Produktnummer ABIN2775866

Produktdetails anti-LIMA1 Antikörper

Target: LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Pferd, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GVLAASMEAK ASSQQEKEDK PAETKKLRIA WPPPTELGSS GSALEEGIKM

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 92%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against LIMA1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human LIMA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 759 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-LIMA1 Antikörper (ABIN2775866)

Maul, Song, Amann, Gerbin, Pollard, Chang: "EPLIN regulates actin dynamics by cross-linking and stabilizing filaments." in: The Journal of cell biology, Vol. 160, Issue 3, pp. 399-407, (2003) (PubMed).

Details zu LIMA1

Target: LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))

Andere Bezeichnung: LIMA1 (LIMA1 Produkte)

Hintergrund: This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.
Alias Symbols: EPLIN, SREBP3
Protein Interaction Partner: TP53, UBC, RPA3, RPA2, RPA1, SUZ12, RNF2, EZH2, BMI1, LRCH3, YWHAQ, YWHAB, PAN2, YWHAE, FMNL1, PAXIP1, ATP6V1B1, APP, UBXN6, LRRK2, ARRB2, ARRB1, SVIL, YWHAG,
Protein Size: 759

Molekulargewicht: 85 kDa

Gen-ID: 51474

NCBI Accession: NM_016357, NP_057441

UniProt: Q9UHB6