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PHD1 Antikörper (N-Term)

EGLN2 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2775821
  • Target Alle PHD1 (EGLN2) Antikörper anzeigen
    PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 58
    • 30
    • 15
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Schwein
    Wirt
    • 69
    • 3
    • 1
    Kaninchen
    Klonalität
    • 65
    • 8
    Polyklonal
    Konjugat
    • 29
    • 7
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PHD1 Antikörper ist unkonjugiert
    Applikation
    • 62
    • 35
    • 16
    • 14
    • 13
    • 9
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Sequenz
    SAGSGTPRAT ATSTTASPLR DGFGGQDGGE LRPLQSEGAA ALVTKGCQRL
    Homologie
    Cow: 79%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against EGLN2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human EGLN2
    Top Product
    Discover our top product EGLN2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 407 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
    Andere Bezeichnung
    EGLN2 (EGLN2 Produkte)
    Synonyme
    egln2 antikoerper, phd2 antikoerper, PHD1 antikoerper, 0610011A13Rik antikoerper, C85656 antikoerper, Hif-p4h-1 antikoerper, Ier4 antikoerper, Phd1 antikoerper, SM-20 antikoerper, HIF-PH1 antikoerper, HPH-1 antikoerper, HPH-3 antikoerper, PHD-1 antikoerper, EIT6 antikoerper, HIFPH1 antikoerper, egl-9 family hypoxia-inducible factor 1 antikoerper, egl-9 family hypoxia inducible factor 2 antikoerper, Egl nine homolog 2 antikoerper, egl-9 family hypoxia-inducible factor 2 L homeolog antikoerper, egl-9 family hypoxia-inducible factor 2 antikoerper, egln1 antikoerper, EGLN2 antikoerper, egln2 antikoerper, egln2.L antikoerper, Egln2 antikoerper
    Hintergrund
    The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms.
    Alias Symbols: EIT6, PHD1, HPH-1, HPH-3, HIFPH1, HIF-PH1
    Protein Interaction Partner: SRPK2, CEP192, IKBKG, FAM46A, EPAS1, A2M, MAGEA11, SIAH2, LPP, WTIP, AJUBA, LIMD1, TRIP6, SPRY2, PRPF19, EGLN3, EGLN2, HIF1A, HIF3A, MOB4, POLR2A,
    Protein Size: 407
    Molekulargewicht
    44 kDa
    Gen-ID
    112398
    NCBI Accession
    NM_053046, NP_444274
    UniProt
    Q96KS0
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis
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