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UBE2L6 Antikörper (N-Term)

UBE2L6 Reaktivität: Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2775687
  • Target Alle UBE2L6 Antikörper anzeigen
    UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
    Bindungsspezifität
    • 10
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
    Wirt
    • 35
    • 6
    Kaninchen
    Klonalität
    • 38
    • 3
    Polyklonal
    Konjugat
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UBE2L6 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 21
    • 14
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    LLLPDQPPYH LKAFNLRISF PPEYPFKPPM IKFTTKIYHP NVDENGQICL
    Homologie
    Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 100%, Rat: 85%, Zebrafish: 85%
    Produktmerkmale
    This is a rabbit polyclonal antibody against UBE2L6. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2L6
    Top Product
    Discover our top product UBE2L6 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 153 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Li, Wang, Yang, Li, Qin, Dong, Zhu, Liang, Liang, Han: "The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8." in: Molecular and cellular biochemistry, Vol. 288, Issue 1-2, pp. 151-7, (2006) (PubMed).

  • Target
    UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
    Andere Bezeichnung
    UBE2L6 (UBE2L6 Produkte)
    Synonyme
    UBE2L6 antikoerper, RIG-B antikoerper, UBCH8 antikoerper, 2810489I21Rik antikoerper, Ubce8 antikoerper, Ubcm8 antikoerper, UbcM8 antikoerper, ubiquitin conjugating enzyme E2 L6 antikoerper, ubiquitin-conjugating enzyme E2L 6 antikoerper, UBE2L6 antikoerper, Ube2l6 antikoerper
    Hintergrund
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Alias Symbols: MGC40331, RIG-B, UBCH8
    Protein Interaction Partner: LONRF1, FBXO31, RBCK1, ARIH2, RBX1, CUL1, SKP1, UBE2L6, UBC, SIAH2, PARK2, RNF144A, UBE3A, RAD23A, ARIH1, SPEN, ISG15, TIMM8A, RAD21, FLT3, ARHGDIA, park, SIAH1, RUNX1, RNF144B, DTX3, RNF19B, TRAF7, TRIM8, RNF122, MUL1, RNF25, RNF150, RNF125, CBLC, TOPORS
    Protein Size: 153
    Molekulargewicht
    18 kDa
    Gen-ID
    9246
    NCBI Accession
    NM_004223, NP_004214
    UniProt
    Q8N5D8
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