PATJ Antikörper (N-Term)

Produktnummer ABIN2775641

Produktdetails anti-PATJ Antikörper

Target: PATJ (INADL) (InaD-Like (INADL))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PATJ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EVMVATLDTQ IADDAELQKY SKLLPIHTLR LGVEVDSFDG HHYISSIVSG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against INADL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human INADL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1801 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PATJ Antikörper (ABIN2775641)

Storrs, Silverstein: "PATJ, a tight junction-associated PDZ protein, is a novel degradation target of high-risk human papillomavirus E6 and the alternatively spliced isoform 18 E6." in: Journal of virology, Vol. 81, Issue 8, pp. 4080-90, (2007) (PubMed).

Details zu PATJ

Target: PATJ (INADL) (InaD-Like (INADL))

Andere Bezeichnung: INADL (INADL Produkte)

Synonyme: wu:fc76h08 antikoerper, si:dz129i22.4 antikoerper, si:busm1-129i22.4 antikoerper, Cipp antikoerper, InaD-like antikoerper, PATJ antikoerper, hINADL antikoerper, Patj antikoerper, Inadl2 antikoerper, RGD1565362 antikoerper, PATJ, crumbs cell polarity complex component antikoerper, patj antikoerper, PATJ antikoerper, Patj antikoerper

Hintergrund: INADL is a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Cipp, FLJ26982, PATJ, hINADL, InaD-like
Protein Interaction Partner: SUMO1, UBC, NEDD8, AMOT, SAV1, AMOTL2, LATS2, YAP1, LATS1, Wwtr1, BAI1, TP53RK, PARD3, Dlg4, ARHGAP17, SUMO2, TJP3, CRB3, PRDM16, NRXN2, ASIC3, MPP5, NLGN2, CNKSR2, PAX6, GLS2, DDX18, KIF1B, CRIPT, SCN4A, CLDN1, CACNG2, GRIN2D, MAPK12, KCNJ10, KCNJ15, KCN
Protein Size: 1801

Molekulargewicht: 196 kDa

Gen-ID: 10207

NCBI Accession: NM_176877, NP_795352

UniProt: Q8NI35