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S1PR5 Antikörper (N-Term)

S1PR5 Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2775525
  • Target Alle S1PR5 Antikörper anzeigen
    S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
    Bindungsspezifität
    • 15
    • 15
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 45
    • 31
    • 30
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Schwein, Rind (Kuh)
    Wirt
    • 76
    • 1
    • 1
    Kaninchen
    Klonalität
    • 77
    • 1
    Polyklonal
    Konjugat
    • 27
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser S1PR5 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 35
    • 26
    • 26
    • 14
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    MESGLLRPAP VSEVIVLHYN YTGKLRGARY QPGAGLRADA VVCLAVCAFI
    Homologie
    Cow: 93%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against EDG8. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human EDG8
    Top Product
    Discover our top product S1PR5 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 398 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))
    Andere Bezeichnung
    EDG8 (S1PR5 Produkte)
    Synonyme
    EDG8 antikoerper, Edg-8 antikoerper, S1P5 antikoerper, SPPR-1 antikoerper, SPPR-2 antikoerper, fd11a07 antikoerper, wu:fd11a07 antikoerper, zgc:92296 antikoerper, edg-8 antikoerper, edg8 antikoerper, s1p5 antikoerper, sppr-1 antikoerper, sppr-2 antikoerper, xts1p5 antikoerper, Edg8 antikoerper, lpB4 antikoerper, zgc:158362 antikoerper, sphingosine-1-phosphate receptor 5 antikoerper, sphingosine-1-phosphate receptor 5a antikoerper, sphingosine-1-phosphate receptor 5b antikoerper, S1PR5 antikoerper, s1pr5a antikoerper, s1pr5 antikoerper, S1pr5 antikoerper, s1pr5b antikoerper
    Hintergrund
    EDG8 is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. It Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). It may play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
    Alias Symbols: Edg-8, S1P5, S1PR5, SPPR-1, SPPR-2, EDG8
    Protein Interaction Partner: TP63, GNA12, GNAO1, GNAI1, SGPP1,
    Protein Size: 398
    Molekulargewicht
    44 kDa
    Gen-ID
    53637
    NCBI Accession
    NM_030760, NP_110387
    UniProt
    Q9H228
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