Follistatin Antikörper (Middle Region)

Produktnummer ABIN2775336

Produktdetails anti-Follistatin Antikörper

Target: Follistatin (FST)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Ziege, Meerschweinchen, Pferd, Kaninchen, Schaf, Rind (Kuh), Zebrafisch (Danio rerio), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Follistatin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ALLKARCKEQ PELEVQYQGR CKKTCRDVFC PGSSTCVVDQ TNNAYCVTCN

Homologie: Cow: 92%, Dog: 100%, Goat: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against FST. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FST

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 317 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Follistatin

Target: Follistatin (FST)

Andere Bezeichnung: FST (FST Produkte)

Hintergrund: Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
Alias Symbols: FS
Protein Interaction Partner: INHBA, BMPR2, BMPR1A, C8orf33, TK1, MEST, INHBE, INHA, FN1, BMP5, TXN,
Protein Size: 317

Molekulargewicht: 35 kDa

Gen-ID: 10468

NCBI Accession: NM_006350, NP_006341

UniProt: B5BU94

Pathways: Negative Regulation of Hormone Secretion