RAD54B Antikörper (N-Term)

Produktnummer ABIN2775215

Produktdetails anti-RAD54B Antikörper

Target: RAD54B (DNA repair and recombination protein RAD54B (RAD54B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Schwein, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD54B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: DAVLIVKGKS FILKNLEGKD IGRGIGYKFK ELEKIEEGQT LMICGKEIEV

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RAD54B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RAD54B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 910 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RAD54B

Target: RAD54B (DNA repair and recombination protein RAD54B (RAD54B))

Andere Bezeichnung: RAD54B (RAD54B Produkte)

Synonyme: RAD54B antikoerper, im:7137737 antikoerper, im:7153525 antikoerper, fsbp antikoerper, rdh54 antikoerper, RDH54 antikoerper, E130016E03Rik antikoerper, Fsbp antikoerper, RGD1306507 antikoerper, RAD54 homolog B (S. cerevisiae) antikoerper, RAD54 homolog B L homeolog antikoerper, RAD54B antikoerper, rad54b antikoerper, rad54b.L antikoerper, Rad54b antikoerper

Hintergrund: RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
Alias Symbols: FSBP, RDH54
Protein Interaction Partner: TCEANC, ATPAF2, ANKRD36BP1, ENKD1, MYO15B, GMCL1, RAD54B, CDC23, SUMO1, PRKAA1, FUS, HECW2, PSMA1, RAD51, NUDT18, NIF3L1, TCEB3, COPS6, SUMO2, UBC, WRN, ZNF580, LNX1, TRAPPC6A, RIBC2, CCDC33, UBE2I, GORASP2, DYRK2, DMC1, CSNK1E, CD2BP2,
Protein Size: 910

Molekulargewicht: 103 kDa

Gen-ID: 25788

NCBI Accession: NM_012415, NP_036547

UniProt: Q9Y620