TJP1 Antikörper (Tight Junction Protein 1 (Zona Occludens 1)) (Middle Region)

Details for Product anti-TJP1 Antibody No. ABIN2774876, Anbieter: Anmelden zum Anzeigen
Antigen
  • ZO-1
  • ZO1
  • zo1
  • tight junction protein 1
  • tight junction protein 1 (zona occludens 1)
  • zonula occludens 1
  • TJP1
  • Tjp1
  • ZO1
Epitop
Middle Region
16
10
5
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
92
32
32
19
10
4
4
3
2
2
1
1
1
1
Wirt
Kaninchen
74
16
3
3
2
Klonalität
Polyklonal
Konjugat
Dieser TJP1 Antikörper ist unkonjugiert
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
74
26
24
23
22
14
13
11
10
8
8
3
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human TJP1
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN985116.
Sequenz QNHVLKQPAV SHPGHRPDKE PNLTYEPQLP YVEKQASRDL EQPTYRYESS
Homologie Dog: 92%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 87%, Pig: 93%, Rabbit: 100%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against TJP1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung TJP1 (TJP1 Antibody Abstract)
Hintergrund TJP1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. TJP1 may be involved in signal transduction at cell-cell junctions.This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: DKFZp686M05161, MGC133289, ZO-1
Protein Interaction Partner: VMP1, RAPGEF2, LATS2, TJP2, PAN2, DTNA, UBC, SCO2, VAPA, VAPB, ZPR1, NOTCH2, NDUFV2, NDUFS6, SUGP1, RTN4, STRN, PARD3, PARD6A, PRKCI, SIRT7, KHDRBS1, ELAVL1, SSTR3, Cdk1, TUBA1C, TUBB4A, VIM, SPTAN1, PLEC, KRT10, KRT8, KRT1, GJA1, FLNA, ANXA6, ACTN1, ACTN
Protein Size: 1668
Molekulargewicht 187 kDa
Gen-ID 7082
NCBI Accession NM_175610, NP_783297
UniProt Q07157
Pathways Carbohydrate Homeostasis, Cell-Cell Junction Organization
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 1668 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Tight Junction Protein 1 (Zona Occludens 1) (TJP1) (Middle Region) antibody (ABIN2774876) anti-Tight Junction Protein 1 (Zona Occludens 1) (TJP1) (Middle Region) antibody
Allgemeine Veröffentlichungen Shen, Weber, Turner: "The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state." in: The Journal of cell biology, Vol. 181, Issue 4, pp. 683-95, 2008 (PubMed).

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