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FBXO5 Antikörper (C-Term)

FBXO5 Reaktivität: Human, Hund, Schwein, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2774700
  • Target Alle FBXO5 Antikörper anzeigen
    FBXO5 (F-Box Protein 5 (FBXO5))
    Bindungsspezifität
    • 12
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    C-Term
    Reaktivität
    • 44
    • 9
    • 9
    • 2
    • 1
    • 1
    Human, Hund, Schwein, Kaninchen
    Wirt
    • 26
    • 18
    Kaninchen
    Klonalität
    • 25
    • 19
    Polyklonal
    Konjugat
    • 20
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FBXO5 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 17
    • 13
    • 10
    • 8
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    ASVQKSAAQT SLKKDAQTKL SNQGDQKGST YSRHNEFSEV AKTLKKNESL
    Homologie
    Dog: 85%, Human: 100%, Pig: 79%, Rabbit: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against FBXO5. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human FBXO5
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    Discover our top product FBXO5 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 447 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Estrabaud, Le Rouzic, Lopez-Vergès, Morel, Belaïdouni, Benarous, Transy, Berlioz-Torrent, Margottin-Goguet: "Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles." in: PLoS pathogens, Vol. 3, Issue 7, pp. e104, (2007) (PubMed).

  • Target
    FBXO5 (F-Box Protein 5 (FBXO5))
    Andere Bezeichnung
    FBXO5 (FBXO5 Produkte)
    Synonyme
    EMI1 antikoerper, FBX5 antikoerper, Fbxo31 antikoerper, 2510044I10Rik antikoerper, C85305 antikoerper, Emi1 antikoerper, emi1 antikoerper, fc65h02 antikoerper, wu:fc65h02 antikoerper, wu:fe06e07 antikoerper, wu:fz79f03 antikoerper, zgc:136397 antikoerper, zgc:158541 antikoerper, fbx5 antikoerper, Fbxo5 antikoerper, ACYPI007854 antikoerper, fbxo5 antikoerper, F-box protein 5 antikoerper, F-box only protein 5 antikoerper, F-box protein 5 L homeolog antikoerper, F-box protein 5 S homeolog antikoerper, FBXO5 antikoerper, Fbxo5 antikoerper, fbxo5 antikoerper, fbxo5.L antikoerper, fbxo5.S antikoerper
    Hintergrund
    FBXO5 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class and is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: EMI1, FBX5, Fbxo31
    Protein Interaction Partner: FBXW11, UBE2S, SKP1, UBC, TPM3, NEDD8, BRCA1, BARD1, ANAPC1, ANAPC11, ANAPC7, ANAPC5, FZR1, ANAPC4, ANAPC2, CDC16, CDC23, CDC27, CDC20, CDK1, MYC, Gm9174, BTRC, PLK1, EVI5,
    Protein Size: 447
    Molekulargewicht
    50 kDa
    Gen-ID
    26271
    NCBI Accession
    NM_012177, NP_036309
    UniProt
    Q9UKT4
    Pathways
    Mitotic G1-G1/S Phases
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