MEF2C Antikörper (Middle Region)

Produktnummer ABIN2774663

Produktdetails anti-MEF2C Antikörper

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio), Hund, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEF2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PPSALSQLGA CTSTHLSQSS NLSLPSTQSL NIKSEPVSPP RDRTTTPSRY

Kreuzreaktivität: Hund, Huhn, Human, Maus, Schwein, Ratte (Rattus)

Homologie: Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MEF2C. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MEF2C

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-MEF2C Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: COLO205 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 473 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MEF2C

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Andere Bezeichnung: MEF2C (MEF2C Produkte)

Synonyme: MEF2C antikoerper, XMEF2C antikoerper, si:ch211-202e12.2 antikoerper, C5DELq14.3 antikoerper, DEL5q14.3 antikoerper, 5430401D19Rik antikoerper, 9930028G15Rik antikoerper, AV011172 antikoerper, Mef2 antikoerper, RGD1563119 antikoerper, id:ibd5026 antikoerper, mef2c antikoerper, wu:fc05b06 antikoerper, zgc:64184 antikoerper, zgc:85726 antikoerper, myocyte enhancer factor 2C antikoerper, MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) antikoerper, myocyte enhancer factor 2cb antikoerper, MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) L homeolog antikoerper, myocyte enhancer factor 2ca antikoerper, MEF2C antikoerper, mef2c antikoerper, mef2cb antikoerper, mef2c.L antikoerper, Mef2c antikoerper, mef2ca antikoerper

Hintergrund: MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. MEF2C may also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Alias Symbols: C5DELq14.3, DEL5q14.3
Protein Interaction Partner: PLA2G12A, UBC, ASCL1, SUMO1, HDAC7, HDAC5, HDAC4, MYOD1, IFRD1, NCOA2, SIRT1, HDAC9, COPS5, YWHAZ, SPTBN1, MAPK7, EPAS1, MAPK14, VGLL2, VGLL4, TWIST2, GATA4, SOX18, EP300, SMAD2, MEF2D, MEF2C, NOTCH1, TEAD1, SP1, CCNB1, CDK1, CSNK2A1, MYOG,
Protein Size: 473

Molekulargewicht: 51 kDa

Gen-ID: 4208

NCBI Accession: NM_002397, NP_002388

UniProt: Q06413

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling