TCF12 Antikörper (Transcription Factor 12) (N-Term)

Details for Product anti-TCF12 Antibody No. ABIN2774659, Anbieter: Anmelden zum Anzeigen
Antigen
  • TCF12
  • CRS3
  • HEB
  • HTF4
  • HsT17266
  • bHLHb20
  • A130037E08Rik
  • ALF1
  • HEBAlt
  • HTF-4
  • ME1
  • REB
  • SCBPA
  • wu:fb74g05
  • wu:fc43e06
  • zgc:110341
  • zgc:85956
  • transcription factor 12
  • transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)
  • TCF12
  • LOC100339415
  • tcf12
  • Tcf12
Epitop
N-Term
24
10
9
9
4
3
3
2
2
2
1
1
Reaktivität
Rind (Kuh), Human, Maus, Schwein, Zebrafisch
91
37
37
9
6
5
4
4
3
2
2
2
2
2
1
Wirt
Kaninchen
72
19
Klonalität
Polyklonal
Konjugat
Dieser TCF12 Antikörper ist unkonjugiert
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
75
41
21
15
13
11
7
6
3
1
1
Optionen
Hersteller
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TCF12
Sequenz QQQRMAAIGT DKELSDLLDF SAMFSPPVNS GKTRPTTLGS SQFSGSGIDE
Kreuzreaktivität Rind (Kuh), Huhn, Human, Maus, Ratte (Rattus)
Homologie Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Zebrafish: 92%
Produktmerkmale This is a rabbit polyclonal antibody against TCF12. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung TCF12 (TCF12 Antibody Abstract)
Hintergrund TCF12 encodes a protein that is a member of the basic helix-loop-helix (bHLH) E-protein family which recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins.The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: HEB, HTF4, HsT17266, bHLHb20
Protein Interaction Partner: TSNAX, STAT5A, SRI, RNASEL, QARS, PSMA1, MLLT6, ID3, CDKN2C, TRIM72, LYSMD1, C6orf165, HEXIM2, ASCL4, MORN4, TWIST2, C16orf45, HOPX, NAGK, C1orf109, SPG21, VPS28, NEUROG3, OSGIN1, CRCP, EDRF1, ARMC8, MAPKBP1, STK16, DGCR6, UBC, TCF21, SOX2, ID2, BMF, MYC,
Protein Size: 706
Molekulargewicht 73 kDa
Gen-ID 6938
NCBI Accession NM_207036, NP_996919
UniProt Q99081
Forschungsgebiet Chromatin and Nuclear Signaling, Transcription Factors
Applikationshinweise WB Suggested Anti-TCF12 Antibody Titration: 0.06 µg/mL
ELISA Titer: 1:1562500
Positive Control: Human Lung.
Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 706 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-TCF12 Antikörper (Transcription Factor 12) (N-Term) (ABIN2774659) WB Suggested Anti-TCF12 Antibody Titration: 0.06ug/ml
ELISA Titer: 1...
Western Blotting (WB) image for anti-TCF12 Antikörper (Transcription Factor 12) (N-Term) (ABIN2774659) Host: Rabbit
Target Name: TCF12
Sample Tissue: Human Fetal Brain
...
Allgemeine Veröffentlichungen Wissmüller, Kosian, Wolf, Finzsch, Wegner: "The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors." in: Nucleic acids research, Vol. 34, Issue 6, pp. 1735-44, 2006 (PubMed).

Zhang, Kalkum, Yamamura, Chait, Roeder: "E protein silencing by the leukemogenic AML1-ETO fusion protein." in: Science (New York, N.Y.), Vol. 305, Issue 5688, pp. 1286-9, 2004 (PubMed).