CD1b Antikörper (N-Term)

Produktnummer ABIN2774371

Produktdetails anti-CD1b Antikörper

Target: CD1b (CD1B)

Bindungsspezifität: N-Term

Reaktivität: Human, Meerschweinchen, Rind (Kuh), Hund, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD1b Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TAIFLKPWSK GNFSDKEVAE LEEIFRVYIF GFAREVQDFA GDFQMKYPFE

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 83%, Horse: 86%, Human: 100%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CD1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 333 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD1b

Target: CD1b (CD1B)

Andere Bezeichnung: CD1B (CD1B Produkte)

Synonyme: CD1 antikoerper, CD1A antikoerper, R1 antikoerper, CD1B3 antikoerper, CD1B antikoerper, CD1-b antikoerper, CD1b molecule antikoerper, T-cell surface glycoprotein CD1b-3 antikoerper, CD1b1 molecule antikoerper, T-cell surface glycoprotein CD1b1 antikoerper, CD1B antikoerper, LOC443423 antikoerper, CD1B1 antikoerper, LOC100720602 antikoerper

Hintergrund: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.
Alias Symbols: CD1, CD1A, MGC125990, MGC125991, R1
Protein Interaction Partner: UBC, PSAP, B2M,
Protein Size: 333

Molekulargewicht: 37 kDa

Gen-ID: 910

NCBI Accession: NM_001764, NP_001755

UniProt: P29016