Spastin Antikörper (Middle Region)

Produktnummer ABIN2774193

Produktdetails anti-Spastin Antikörper

Target: Spastin (SPAST)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Meerschweinchen, Ziege, Zebrafisch (Danio rerio), Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Spastin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RVLVMGATNR PQELDEAVLR RFIKRVYVSL PNEETRLLLL KNLLCKQGSP

Homologie: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SPAST. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SPAST

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Spastin

Target: Spastin (SPAST)

Andere Bezeichnung: SPAST (SPAST Produkte)

Synonyme: CG5977 antikoerper, D-spastin antikoerper, Dmel\\CG5977 antikoerper, Dspastin antikoerper, Spas antikoerper, zgc:85952 antikoerper, SPAST antikoerper, spg4 antikoerper, LOC100224472 antikoerper, ADPSP antikoerper, FSP2 antikoerper, SPG4 antikoerper, Spg4 antikoerper, mKIAA1083 antikoerper, spastin antikoerper, spastin S homeolog antikoerper, spas antikoerper, spast antikoerper, SPAST antikoerper, Spast antikoerper, spast.S antikoerper

Hintergrund: This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.
Protein Interaction Partner: HECW2, ALB, VCP, CHMP1B, IST1, ELAVL1, SSNA1, RTN1,
Protein Size: 498

Molekulargewicht: 54 kDa

Gen-ID: 6683

Pathways: Microtubule Dynamics, M Phase, Regulation of Cell Size