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CAMKK2 Antikörper (N-Term)

CAMKK2 Reaktivität: Human, Maus, Ratte, Schwein, Meerschweinchen, Rind (Kuh), Kaninchen, Hund, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2774040
  • Target Alle CAMKK2 Antikörper anzeigen
    CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
    Bindungsspezifität
    • 17
    • 16
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 62
    • 40
    • 23
    • 17
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Schwein, Meerschweinchen, Rind (Kuh), Kaninchen, Hund, Zebrafisch (Danio rerio)
    Wirt
    • 69
    • 7
    Kaninchen
    Klonalität
    • 71
    • 5
    Polyklonal
    Konjugat
    • 37
    • 7
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CAMKK2 Antikörper ist unkonjugiert
    Applikation
    • 71
    • 35
    • 21
    • 14
    • 10
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    GGLAAGGSLD MNGRCICPSL PYSPVSSPQS SPRLPRRPTV ESHHVSITGM
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%, Zebrafish: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CAMKK2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CAMKK2
    Top Product
    Discover our top product CAMKK2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 498 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
    Andere Bezeichnung
    CAMKK2 (CAMKK2 Produkte)
    Synonyme
    CAMKK antikoerper, CAMKKB antikoerper, 6330570N16Rik antikoerper, AW061083 antikoerper, mKIAA0787 antikoerper, camk2b antikoerper, fj90d04 antikoerper, wu:fj90d04 antikoerper, si:dkey-174n20.2 antikoerper, CAMKK2 antikoerper, calcium/calmodulin dependent protein kinase kinase 2 antikoerper, calcium/calmodulin-dependent protein kinase kinase 2, beta antikoerper, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 antikoerper, calcium/calmodulin dependent protein kinase II beta antikoerper, calcium/calmodulin-dependent protein kinase kinase 2 antikoerper, CAMKK2 antikoerper, Camkk2 antikoerper, camk2b1 antikoerper, CAMK2B antikoerper, camkk2 antikoerper
    Hintergrund
    CAMKK2 is a calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 seems to be involved in hippocampal activation of CREB1.The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases.
    Alias Symbols: CAMKK, CAMKKB, KIAA0787, MGC15254
    Protein Interaction Partner: HSP90AA1, APP, UBC, NEDD4, CEP63, ESYT2, FANCI, OBSL1, ATG4B, XPOT, GCN1L1, IQGAP2, SMC3, SLC25A11, SMC1A, PRKDC, PRKAG1, PRKAA2, IRAK1, FLNC, FLNA, MAPK14, CALM1, CAMK4, CAMK1, PRKACA, SGK1,
    Protein Size: 498
    Molekulargewicht
    55 kDa
    Gen-ID
    10645
    NCBI Accession
    NM_153500, NP_705720
    UniProt
    Q96RR4
    Pathways
    AMPK Signaling
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