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CYP46A1 Antikörper (C-Term)

CYP46A1 Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen, Ziege WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2773829
  • Target Alle CYP46A1 Antikörper anzeigen
    CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))
    Bindungsspezifität
    • 28
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 32
    • 26
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen, Ziege
    Wirt
    • 38
    • 2
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser CYP46A1 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 24
    • 24
    • 10
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    YVMGRMDTYF EDPLTFNPDR FGPGAPKPRF TYFPFSLGHR SCIGQQFAQM
    Homologie
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CYP46A1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CYP46A1
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    Discover our top product CYP46A1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 500 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))
    Andere Bezeichnung
    CYP46A1 (CYP46A1 Produkte)
    Synonyme
    CP46 antikoerper, CYP46 antikoerper, CYP46A1 antikoerper, zgc:109896 antikoerper, MGC147389 antikoerper, Cyp46 antikoerper, cytochrome P450 family 46 subfamily A member 1 antikoerper, cytochrome P450 family 46 subfamily A member 1 L homeolog antikoerper, cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 antikoerper, cytochrome P450, family 46 antikoerper, cytochrome P450 46A1 antikoerper, cytochrome P450, family 46, subfamily a, polypeptide 1 antikoerper, cholesterol 24-hydroxylase antikoerper, cytochrome P450, family 46, subfamily A, polypeptide 1 antikoerper, CYP46A1 antikoerper, cyp46a1.L antikoerper, cyp46a1.1 antikoerper, cyp46a1 antikoerper, PTRG_08343 antikoerper, PTRG_09667 antikoerper, Cyp46a1 antikoerper, Sgly_1093 antikoerper
    Hintergrund
    CYP46A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CP46, CYP46
    Protein Size: 500
    Molekulargewicht
    57 kDa
    Gen-ID
    10858
    NCBI Accession
    NM_006668, NP_006659
    UniProt
    Q9Y6A2
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