KRT18 Antikörper (Keratin 18) (FITC)

Details for Product anti-KRT18 Antibody No. ABIN272330, Anbieter: Anmelden zum Anzeigen
Antigen
  • CK18
  • K18
  • Krt1-18
  • CYK18
  • DreK18
  • cb83
  • dapk1
  • sb:cb83
  • wu:fa13f02
  • wu:fb36b04
  • krt18
  • MGC64569
  • MGC75922
  • KRT18
  • krtt1c6
  • zgc:66015
  • keratin 18
  • keratin 18, type I L homeolog
  • keratin 18, type I
  • keratin, type I cytoskeletal 18 pseudogene
  • keratin, type I cytoskeletal 18
  • keratin, type I cytoskeletal 18-like
  • K18, simple type I keratin
  • Keratin, type I cytoskeletal 18
  • zgc:77517
  • Krt18
  • KRT18
  • krt18
  • krt18.L
  • LOC693413
  • LOC700110
  • LOC700569
  • LOC704517
  • LOC100136778
  • k1c18
  • LOC100008885
  • zgc:77517
Reaktivität
Human
944
201
171
69
64
41
35
34
26
26
22
20
18
15
12
7
7
5
4
4
3
3
2
2
1
1
1
Wirt
Maus
695
275
12
11
4
3
2
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser KRT18 Antikörper ist konjugiert mit FITC
52
47
22
18
17
17
14
14
14
14
14
14
14
14
14
11
11
8
4
3
3
3
3
3
3
3
3
2
2
2
1
Applikation
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
655
465
385
345
330
300
222
177
126
40
26
18
18
14
11
9
3
2
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Human breast carcinoma cell line PMC-42.
Klon DC-10
Isotyp IgG1
Spezifität The antibody DC-10 reacts with Cytokeratin 18 (45 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
Kreuzreaktivität (Details) Species reactivity (tested):Human.
Reinigung Protein A Chromatography
Andere Bezeichnung Cytokeratin 18 (KRT18 Antibody Abstract)
Hintergrund Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families. Cytokeratin 18 belongs to type I family (acidic cytokeratins).Synonyms: CK18, CYK18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, K18, KRT18, Keratin 18, Keratin type I cytoskeletal 18, Keratin-18
Gen-ID 3875
NCBI Accession NP_000215
UniProt P05783
Forschungsgebiet Signaling, Cytoskeleton, Extracellular Matrix
Pathways Apoptose, Caspase Kaskade in der Apoptose
Applikationshinweise Further Comments: Flow Cytometry analysis and Immunofluorescence (5-10 μg/mL).
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 0.1 mg/mL
Buffer PBS, 15 mM Sodium Azide, 0.2 % (w/v) high-grade BSA (Protease free)
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Produkt verwendet in: Vojt?sek, Stasková, Nenutil, Lauerová, Kovarík, Rejthar, Bártková, Bártek: "Monoclonal antibodies recognizing different epitopes of cytokeratin No.18." in: Folia biologica, Vol. 35, Issue 6, pp. 373-82, 1990 (PubMed).

Kovarík, Rejthar, Lauerová, Vojt?sek, Bártková: "Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread." in: International journal of cancer. Supplement = Journal international du cancer. Supplement, Vol. 3, pp. 50-5, 1989 (PubMed).

Allgemeine Veröffentlichungen Lauerová, Kovarik, Bártek, Rejthar, Vojt?sek: "Novel monoclonal antibodies defining epitope of human cytokeratin 18 molecule." in: Hybridoma, Vol. 7, Issue 5, pp. 495-504, 1989 (PubMed).