DLGAP1 Antikörper

Produktnummer ABIN272131

Produktdetails anti-DLGAP1 Antikörper

Target: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of SAPAP1 protein. (region surrounding Glu817)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 10000. Western blot: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu DLGAP1

Target: DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Andere Bezeichnung: DLGAP1 / SAPAP1 (DLGAP1 Produkte)

Synonyme: DKFZp469D0713 antikoerper, gkap antikoerper, sapap1 antikoerper, DAP-1 antikoerper, DAP-1-ALPHA antikoerper, DAP-1-BETA antikoerper, GKAP antikoerper, SAPAP1 antikoerper, hGKAP antikoerper, 4933422O14Rik antikoerper, 9630002F18 antikoerper, AI845682 antikoerper, AI848168 antikoerper, BB075781 antikoerper, D17Bwg0511e antikoerper, GKAP/SAPAP antikoerper, GKPA/SAPAP antikoerper, Gkap antikoerper, Sapap1 antikoerper, mKIAA4162 antikoerper, DLG associated protein 1 antikoerper, discs, large (Drosophila) homolog-associated protein 1 antikoerper, disks large-associated protein 1 antikoerper, discs, large homolog-associated protein 1 antikoerper, discs, large (Drosophila) homolog-associated protein 1b antikoerper, DLGAP1 antikoerper, LOC100408093 antikoerper, LOC100548434 antikoerper, dlgap1 antikoerper, Dlgap1 antikoerper, dlgap1b antikoerper

Hintergrund: Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membraneassociated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-α, DAP-1-β, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP1, through the guanylate kinase domain. SAPAP1 is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. N-terminal splice variants of SAPAP1 are expressed as 95 and 130 kDa proteins. SAPAP1 is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.Synonyms: DAP-1, DAP1, Disks large-associated protein 1, GKAP, Guanylate kinase-associated protein, PSD-95/SAP90-binding protein 1, SAP90/PSD-95-associated protein 1

Molekulargewicht: approx. 108 kDa

Gen-ID: 9229

NCBI Accession: NP_001003809

UniProt: O14490