ATG10 Autophagy Related 10 Homolog (S. Cerevisiae) (ATG10) Antikörper

Antigen: ATG10 Autophagy Related 10 Homolog (S. Cerevisiae) (ATG10)

Synonyme: APG10, Agp10, Apg10l, Apg10p, Atg10l, AI852123, 5330424L23Rik, 5430428K15Rik, APG10L, ATG10, MGC123341, im:7153729, zgc:123341, MGC138057, autophagy 10, Atg10

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunfluoreszenz (IF)

Produktnummer: ABIN271670

Produktbeschreibung

Weitere Bezeichnung: APG10L / ATG10

Gen-ID: 83734

Immunogen: A synthetic peptide corresponding to the C-terminal of human APG10 protein has beenused as the immunogen.

Beschreibung: A major contributor to cellular homeostasis is the ability of the cell to strike a balancebetween the formation and degradation/removal of its cellular components. This processof internal cellular turn-over is called autophagy (self-eating), and is facilitated by apathway of around 16 interacting proteins in the human. APG10 interacts with LC3A tofacilitate the conjugation of ATG12 to ATG5. APG10 is also able to directly interacteither with ATG5 or ATG7A. A disruption to the autophagic process is now associatedwith the progression of several cancers, neurodegenerative disorders and cardiacpathologies. Alternate Names: anti-Apg 10 antibody, anti-APG 10L antibody, anti-APG10 autophagy 10 like antibody,anti-APG10 like antibody, anti-APG10L antibody, anti-ATG 10 antibody, anti-ATG10antibody, anti-ATG10 autophagy related 10 homolog (S. cerevisiae) antibody,anti-ATG10 autophagy related 10 homolog antibody, anti-Autophagy related protein 10antibody, anti-DKFZP586I0418 antibody, anti-FLJ13954 antibody, anti-pp12616antibody. Related Diseases: Autophagy

Spezifität: IHC, WB and ELISA confirmed the specificity for APG10. Species Reactivity: Reacts with Human.

Anwendungen

Applikationshinweise: Suggested working dilutions: immunohistochemistry 1:100 to 1:1000,immunofluorescence 1:100 to 1:1000

Buffer: Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material. Preservative: No Preservative.

Lagerung: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Wan, Gong, Qin et al.: "Large-scale cDNA transfection screening for genes related to cancer development and progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 44, pp. 15724-9, 2004 (PubMed).