Die von Ihnen gewünschte Seite kann leider nicht angezeigt werden.
In den Warenkorb
Bestellen Sie auch über:
 |
+49 (0)241 95 163 153 |
 |
+49 (0)241 95 163 155 |
X-Linked Inhibitor of Apoptosis (XIAP) Antikörper
| Antigen | X-Linked Inhibitor of Apoptosis (XIAP) |
| Synonyme | API3, ILP1, MIHA, XLP2, BIRC4, XIAP, birc4, xiap, MGC107868, xxiap |
| Klonalität | Polyklonal |
| Wirt |
 Alternativen Kaninchen |
| Reaktivität |
Alternativen Human, Maus, Ratte (Rattus) |
| Applikation |
Alternativen Immunhistochemie (Gefrierschnitte) (IHC (fro)), Immunfluoreszenz (IF), Immunpräzipitation (IP), Western Blot (WB)
|
| Produktnummer | ABIN269889 |
| Menge | 50 µg (0.2 mg/ml) (Varianten) |
| Preis | 330,00 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
|
| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | IAP3 / BIRC4 |
| Gen-ID | 331, 63879 |
| Immunogen | Synthetic peptide surrounding amino acid 230 of human XIAP (ID# BV-94). |
| Isotyp | IgG (Passende Sekundärantikörper) |
| Beschreibung | The human X-chromosome-linked inhibitor of apoptosis protein (XIAP) is a majormember of the inhibitor of apoptosis (IAP) family. XIAP functions by direct binding andinhibition of several caspases, including caspase-3, caspase-7 and caspase-9. Duringapoptosis XIAP is specifically cleaved by caspase-3 and partially loses its function. Inaddition to blocking the apoptosis signaling pathway, XIAP can also bind several otherproteins in the bone morphogenetic protein (BMP) signaling pathway and act as acoupler between the membrane BMP receptor and the TAB1-TAK1 complex by bindingto these proteins. Alternate Names: Anti-AP 13 antibody, Anti-API3 antibody, Anti-Apoptosis Inhibitor 3 antibody,Anti-Baculoviral IAP repeat containing 4 antibody, Anti-Baculoviral IAP RepeatContaining Protein 4 antibody, Anti-BIRC 4 antibody, Anti-BIRC4 antibody, Anti-HILPantibody, Anti-IAP 3 antibody, Anti-IAP like protein antibody, Anti-IAP3 antibody,Anti-ILP 1 antibody, Anti-ILP1 antibody, Anti-Inhibitor of apoptosis protein 3 antibody,Anti-Inhibitor of Apoptosis X Linked antibody, Anti-Mammalian IAP Homologue Aantibody, Anti-MIHA antibody, Anti-X linked IAP antibody, Anti-X linked inhibitor ofapoptosis antibody, Anti-X linked inhibitor of apoptosis protein antibody. |
| Spezifität | This antibody detects the 53 kDa human XIAP protein. It does not cross-react with otherapoptosis inhibitors. Species Reactivity: Cross-reacts with Human, Mouse and Rat. Not yet tested in other species. |
Anwendungen
| Applikationshinweise | Suggested working dilutions: immunofluorescence 1:2000,Western Blot 1.0-4.0 ug/ml,Immunocytochemistry 1:2000. Positive Controls: Jurkat cell lysate |
| Konzentration | 0.2 mg/ml |
| Buffer | PBS, pH 7.2, containing 50% glycerol, 1% BSA. Preservative: 0.02% sodium azide |
| Lagerung | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Forschungsgebiet | Krebs, Apoptose/Nekrose |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
Alternativen zu Antigen "X-Linked Inhibitor of Apoptosis (XIAP)", Typ "Antikörper" finden
| Wirte | Kaninchen (30), Maus (6), Ziege (1) |
| Reaktivitäten | Human (37), Maus (18), Ratte (Rattus) (9), Schwein (2), Kaninchen (2), Säugetiere (1) |
| Applikationen | Western Blot (WB) (36), Immunhistochemie (Paraffinschnitte) (IHC (p)) (20), Enzyme Immunoassay (EIA) (10), Immunpräzipitation (IP) (9), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (8), ELISA (Detektionsantikörper) (3), Immunfluoreszenz (IF) (3), Dot Blot (Dot) (1), ELISA (1), Immunhistochemie (IHC) (1) |
| Epitope | AA 163-230 (4), C-Term (3), N-Term (2), AA 241-260 (1), AA 75-226 (1) |
