Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antikörper

Antigen: Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

Synonyme: TIM3, KIM-3, TIMD3, Tim-3, FLJ14428, HAVCR2, MGC140131

Klonalität: Polyklonal

Wirt: Ziege

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Western Blot (WB)

Produktnummer: ABIN269847

Produktbeschreibung

Weitere Bezeichnung: TIMD3 / HAVCR2

Gen-ID: 84868

Swiss-Prot: NP_1161713

Immunogen: Synthetic peptide: C-KWYSHSKEKIQN, representing the internal regionof the humanprotein according to NP_116171.3. Reference Sequence: NP_116171.3.

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associatedcytokines are involved in cell-mediated immunity to intracellular pathogens anddelayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control ofextracellular helminthic infections and the promotion of atopic and allergic diseases. The2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cellsurface protein that regulates macrophage activation and enhances the severity ofexperimental autoimmune encephalomyelitis in mice.[supplied by OMIM]. Alternate Names: anti-HAVCR2 antibody, anti-hepatitis A virus cellular receptor 2 antibody, anti-FLJ14428antibody, anti-KIM-3 antibody, anti-TIM3 antibody, anti-TIMD3 antibody, anti-Tim-3antibody, anti-T cell immunoglobulin mucin 3 antibody, anti-T cell immunoglobulinmucin-3 antibody, anti-kidney injury molecule-3 antibody.

Spezifität: Species Reactivity: Human. Other species not tested. Reactivity expected based upon sequencehomology: Dog.

Anwendungen

Applikationshinweise: Peptide ELISA: antibody detection limit dilution 1:32,000.Western Blot: Approx35kDa band observed in Human Tonsil, Thymus, Lymph Node and Spleen lysates(calculated MW of 33.4kDa according to NP_116171.3). Recommended concentration:0.3-1.0ug/ml.

Konzentration: 0.5 mg/ml

Buffer: Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA. Preservative: Contains sodium azide.

Lagerung: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar