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Bone Morphogenetic Protein 4 (BMP4) Antikörper
| Antigen | Bone Morphogenetic Protein 4 (BMP4) |
| Synonyme | ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, Bmp-4, Bmp2b, Bmp2b1, Bmp2b-1, BOMPR4A, bmp-4, zbmp-4, MGC100779, zgc:100779, BMP4, BMP-4, xbmp4, XBMP-4, Bmp4, MGC127497, zyme, bmp2b, bmp2b1, bmp4 |
| Klonalität | Monoklonal (66119-11) |
| Wirt |
 Alternativen Maus |
| Reaktivität |
Alternativen Human |
| Applikation |
Alternativen Enzyme Immunoassay (EIA), Western Blot (WB)
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| Produktnummer | ABIN269693 |
| Menge | 0.1 mg (0.5 mg/ml) |
| Preis | 330,00 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | BMP4 |
| Gen-ID | 652 |
| Immunogen | Recombinant full length protein expressed in NSO cells (Human). |
| Isotyp | IgG2b (Passende Sekundärantikörper) |
| Klon | 66119-11 |
| Beschreibung | Bone Morphogenic Proteins (BMP) are members of the TGF-beta superfamily that affectbone and cartilage formation (1,2,3). Mature BMPs are 30-38 kDa proteins that assumea TGF-beta -like cysteine knot configuration.Lovostatin increases bone formation byturning on the bmp-2 gene (4). BMPs stimulate the production of specific bone matrixproteins and alter stromal cell and osteoclast proliferation (5,6). BMPs may also be animportant factor for development of the viscera, with roles in cell proliferation, apoptosis,differentiation, and morphogenesis (1,7).BMPs appear to be responsible for normaldorsal/ventral patterning. Like TGF-beta, BMPs bind to a type II receptor, which thenrecruits the transducing type I receptor unit, activating the Smad protein signalingpathway (8,9,10). Alternate Names: Anti-BMP 2B antibody, Anti-BMP 4 antibody, Anti-BMP2B antibody, Anti-BMP2B1antibody, Anti-Bone morphogenetic protein 4 antibody, Anti-DVR4 antibody, Anti-ZYMEantibody. |
| Spezifität | Monoclonal Anti-BMP-4 neutralizes human BMP-4, and recognizes recombinant humanBMP-4 by ELISA and immunoblotting. The antibody shows approximately 5%cross-reactivity with recombinant human BMP-2, recombinant mouse BMP RIA andBMP-RIB. Species Reactivity: Cross-reacts with Human.Not yet tested in other species. Localization: Secreted, extracellular matrix. |
Anwendungen
| Applikationshinweise | Suggested working dilutions: ELISA 0.5-1.0 ug/ml,Western Blot 1-2 ug/ml,Neut, 1-3 ug/ml |
| Konzentration | 0.5 mg/ml |
| Buffer | No Buffer |
| Lagerung | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Forschungsgebiet | Organogenese, Wachstumsfaktoren, Angiogenese, Signaltransduktion |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
Alternativen zu Antigen "Bone Morphogenetic Protein 4 (BMP4)", Typ "Antikörper" finden
| Wirte | Kaninchen (46), Maus (25) |
| Reaktivitäten | Human (63), Maus (26), Ratte (Rattus) (21), Huhn (3), Kaninchen (2), Rind (Kuh) (1), Hund (1), Schwein (1), Xenopus laevis (1) |
| Applikationen | Western Blot (WB) (42), Immunhistochemie (Paraffinschnitte) (IHC (p)) (23), Durchflusszytometrie (FACS) (19), Immunfluoreszenz (IF) (19), ELISA (18), Enzyme Immunoassay (EIA) (5), Immunzytochemie (ICC) (3), Immunhistochemie (IHC) (3), Immunpräzipitation (IP) (3), Neutralisierung (Neut) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (2), Blocking Antibody (Inhibition) (1), Funktionale Studien (Func) (1), Immunoelectron Microscopy (IEM) (1) |
| Konjugate | Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |
| Epitope | N-Term (1) |
