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CD14 Molecule (CD14) Antikörper (Biotin)
| Antigen | CD14 Molecule (CD14) |
| Synonyme | CD14 |
| Klonalität | Monoklonal (MEM-18) |
| Wirt |
Alternativen Maus |
| Konjugat |
Alternativen Biotin |
| Applikation |
Alternativen Enzyme Immunoassay (EIA), Durchflusszytometrie (FACS), Immunpräzipitation (IP), Western Blot (WB)
|
| Produktnummer | ABIN269006 |
| Menge | 0.1 mg (1 mg/ml) |
| Preis | 350,00 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
|
| Verfügbarkeit | Lieferung in 7 bis 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | CD14 |
| Immunogen | A crude mixture of human urinary proteins precipitated by ammonium sulphate from theurine of a patient suffering from proteinuria. |
| Isotyp | IgG1 |
| Klon | MEM-18 |
| Beschreibung | CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDaglycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte orliver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules arecritical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confersLPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated withinflammatory infectious diseases and high mortality in gram negative shock. CD14 alsoappears to be involved in clearance of gram-negative bacteria via its high affinity bindingto LPS-LPB complexes. Alternate Names: anti-CD14 antigen antibody, anti-Lipopolysaccharide receptor antibody, anti-LPSRantibody, anti-Monocyte Differentiation Antigen 14 antibody, anti-Myeloid cell specificleucine rich glycoprotein antibody. |
| Spezifität | Species Reactivity: Cross-reacts with Human and non Human Primates. Localization: Cytoplasmic. Attached to the membrane by a GPI anchor. |
Anwendungen
| Applikationshinweise | Suggested working dilutions: flow cytometry / FACS analysis 1:1 - 1:1000 |
| Konzentration | 1 mg/ml |
| Buffer | PBS. pH 7.4. Preservative: 15mM Sodium Azide. |
| Lagerung | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Forschungsgebiet | Stammzellen, Angeborene Immunität, Hämopoetische Vorläufer, Hämatopoetische Stammzellen, CD Antigene, Oberflächenrezeptoren der Immunzellen , Apoptose/Nekrose, Immunologie, Inflammation |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
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