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CD56 Antikörper

NCAM1 Reaktivität: Human FACS, IHC (f) Wirt: Maus Monoclonal R19 unconjugated
Produktnummer ABIN2689855
  • Target Alle CD56 (NCAM1) Antikörper anzeigen
    CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
    Reaktivität
    • 259
    • 72
    • 67
    • 26
    • 18
    • 14
    • 12
    • 10
    • 10
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    Human
    Wirt
    • 177
    • 89
    • 3
    • 1
    Maus
    Klonalität
    • 195
    • 74
    • 1
    Monoklonal
    Konjugat
    • 98
    • 15
    • 14
    • 13
    • 11
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD56 Antikörper ist unkonjugiert
    Applikation
    • 166
    • 134
    • 59
    • 48
    • 48
    • 37
    • 33
    • 31
    • 27
    • 26
    • 16
    • 14
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Marke
    BD Pharmingen™
    Produktmerkmale
    The R19-760 monoclonal antibody specifically binds to NCAM-1 (Neural cell adhesion molecule 1) that is also known as CD56 and NKH1. NCAM-1 is a heavily glycosylated transmembrane protein and a member of the Ig supergene family. NCAM-1 represents an isoform of the neural cell adhesion molecule (NCAM). In the hematopoietic system, it is present on approximately 10 % to 25 % of peripheral blood lymphocytes. It is expressed on natural killer (NK) cells and a subset of T cells, NKT cells. It is not expressed on myeloid cells, erythrocytes or B cells. This molecule appears to function as an adhesion molecule and can serve as a panspecific NK-cell marker. The R19-760 antibody recognizes an epitope in the NCAM-1 (CD56) extracellular domain that resists destruction due to cellular fixation with BD Phosflow™ Lyse/Fix Buffer and permeabilization with BD Phosflow™ Perm Buffer III. Analyses of NCAM-1 (CD56) expression by Immunohistochemistry and

    BD Pharmingen™ Purified Mouse Anti-Human NCAM-1 (CD56) - Purified - Clone R19-760 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human NCAM1 Recombinant Protein
    Klon
    R19
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product NCAM1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C.
  • Gerosa, Baldani-Guerra, Nisii, Marchesini, Carra, Trinchieri: "Reciprocal activating interaction between natural killer cells and dendritic cells." in: The Journal of experimental medicine, Vol. 195, Issue 3, pp. 327-33, (2002) (PubMed).

    Galandrini, Tassi, Mattia, Lenti, Piccoli, Frati, Santoni: "SH2-containing inositol phosphatase (SHIP-1) transiently translocates to raft domains and modulates CD16-mediated cytotoxicity in human NK cells." in: Blood, Vol. 100, Issue 13, pp. 4581-9, (2002) (PubMed).

    Cooper, Fehniger, Caligiuri: "The biology of human natural killer-cell subsets." in: Trends in immunology, Vol. 22, Issue 11, pp. 633-40, (2001) (PubMed).

    Bennett, Zatsepina, Zamai, Azzoni, Mikheeva, Perussia: "Definition of a natural killer NKR-P1A+/CD56-/CD16- functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12." in: The Journal of experimental medicine, Vol. 184, Issue 5, pp. 1845-56, (1996) (PubMed).

    Lanier, Chang, Azuma, Ruitenberg, Hemperly, Phillips: "Molecular and functional analysis of human natural killer cell-associated neural cell adhesion molecule (N-CAM/CD56)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 12, pp. 4421-6, (1991) (PubMed).

    Nitta, Yagita, Sato, Okumura: "Involvement of CD56 (NKH-1/Leu-19 antigen) as an adhesion molecule in natural killer-target cell interaction." in: The Journal of experimental medicine, Vol. 170, Issue 5, pp. 1757-61, (1989) (PubMed).

    Lanier, Testi, Bindl, Phillips: "Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule." in: The Journal of experimental medicine, Vol. 169, Issue 6, pp. 2233-8, (1989) (PubMed).

    Schubert, Zimmermann, Cramer, Starzinski-Powitz: "Lymphocyte antigen Leu-19 as a molecular marker of regeneration in human skeletal muscle." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 1, pp. 307-11, (1989) (PubMed).

    Cunningham, Hemperly, Murray, Prediger, Brackenbury, Edelman: "Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing." in: Science (New York, N.Y.), Vol. 236, Issue 4803, pp. 799-806, (1987) (PubMed).

    Edelman: "Cell adhesion molecules in the regulation of animal form and tissue pattern." in: Annual review of cell biology, Vol. 2, pp. 81-116, (1987) (PubMed).

    Phillips, Lanier: "Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis." in: The Journal of experimental medicine, Vol. 164, Issue 3, pp. 814-25, (1986) (PubMed).

    Lanier, Le, Civin, Loken, Phillips: "The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 136, Issue 12, pp. 4480-6, (1986) (PubMed).

  • Target
    CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
    Andere Bezeichnung
    NCAM-1 CD56 (NCAM1 Produkte)
    Synonyme
    CD56 antikoerper, MSK39 antikoerper, NCAM antikoerper, fj56g09 antikoerper, ncam antikoerper, ncam1 antikoerper, wu:fj56g09 antikoerper, NCAM1 antikoerper, n-cam antikoerper, E-NCAM antikoerper, NCAM-1 antikoerper, Ncam antikoerper, Cd56 antikoerper, N-CAM antikoerper, N-CAM-1 antikoerper, NCAM-C antikoerper, NCAMC antikoerper, N-CAM-1-B antikoerper, NCAM-1-B antikoerper, ncam1-a antikoerper, ncam1-b antikoerper, neural cell adhesion molecule 1 antikoerper, neural cell adhesion molecule 1a antikoerper, neural cell adhesion molecule 1 S homeolog antikoerper, neural cell adhesion molecule 1 L homeolog antikoerper, NCAM1 antikoerper, ncam1a antikoerper, ncam1 antikoerper, LOC100085373 antikoerper, ncam1.S antikoerper, Ncam1 antikoerper, ncam1.L antikoerper
    Hintergrund
    Synonyms: N-CAM-1, Neural cell adhesion molecule 1, NKH1, MSK39, Leu-19
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