Integrin beta 7 Antikörper

Produktnummer ABIN2689794

Produktdetails anti-Integrin beta 7 Antikörper

Target: Integrin beta 7 (ITGB7)

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 7 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Marke: BD Pharmingen™

Produktmerkmale: FIB504 reacts with mouse integrin β7 subunit (130 kD) but also cross reacts with human integrin β7. Integrin β7 associates with α4 (CD49d) expressed on subsets of lymphocytes and thymus. It also associates with αIEL (CD103) expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Integrin β7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. Profile of peripheral blood lymphocytes analyzed on a FACScan

BD Pharmingen™ Purified Rat Anti-Human Integrin β7 - Purified - Clone FIB504 - Isotype Rat IgG2a, κ - Reactivity Hu - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Klon: FIB504

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-Integrin beta 7 Antikörper (ABIN2689794)

Butcher, Picker: "Lymphocyte homing and homeostasis." in: Science (New York, N.Y.), Vol. 272, Issue 5258, pp. 60-6, (1996) (PubMed).

Teague, Lazarovits, McIntyre: "Integrin alpha 4 beta 7 co-stimulation of human peripheral blood T cell proliferation." in: Cell adhesion and communication, Vol. 2, Issue 6, pp. 539-47, (1995) (PubMed).

Erle, Briskin, Butcher, Garcia-Pardo, Lazarovits, Tidswell: "Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 153, Issue 2, pp. 517-28, (1994) (PubMed).

Berlin, Berg, Briskin, Andrew, Kilshaw, Holzmann, Weissman, Hamann, Butcher: "Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1." in: Cell, Vol. 74, Issue 1, pp. 185-95, (1993) (PubMed).

Details zu Integrin beta 7

Target: Integrin beta 7 (ITGB7)

Andere Bezeichnung: Integrin Beta7 (ITGB7 Produkte)

Synonyme: Ly69 antikoerper, integrin beta 7 antikoerper, integrin subunit beta 7 antikoerper, integrin, beta 7 antikoerper, Itgb7 antikoerper, ITGB7 antikoerper

Pathways: Integrin Complex