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CD59 Antikörper (Biotin)

CD59 Reaktivität: Human FACS Wirt: Maus Monoclonal p282 Biotin
Produktnummer ABIN2689347
  • Target Alle CD59 Antikörper anzeigen
    CD59
    Reaktivität
    • 139
    • 14
    • 9
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 91
    • 69
    • 6
    • 4
    Maus
    Klonalität
    • 98
    • 69
    • 1
    Monoklonal
    Konjugat
    • 79
    • 21
    • 16
    • 13
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD59 Antikörper ist konjugiert mit Biotin
    Applikation
    • 102
    • 70
    • 46
    • 41
    • 31
    • 28
    • 25
    • 15
    • 15
    • 14
    • 13
    • 12
    • 11
    • 11
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    Flow Cytometry (FACS)
    Marke
    BD Pharmingen™
    Produktmerkmale
    Reacts with CD59, a 19 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein, expressed on hematopoietic and non-hematopoietic cells. Because of its role in interaction with complement activated products, CD59 has been termed membrane-attack-complex-inhibitory factor (MACIF), homologus restriction factor (HRF20), membrane inhibitor of reactive lysis (MIRL) and protectin. It inhibits the cytolytic activity of complement by binding to C8 and C9, thereby blocking the assembly of the membrane attack complex. CD59 also participates in spontaneous T-cell/erythrocyte adhesion, interacts with CD2 and plays a role in T-cell activation. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of glycosylphosphatidylinositol (GPI) anchor-defective mutant cell line analyzed on a FACScan Profile of K562 cells expressing glycosylphosphatidylinositol (GPI) anchor protein analyzed on a FACScan

    BD Pharmingen™ Biotin Mouse Anti-Human CD59 - Biotin - Clone p282 (H19) - Isotype Mouse IgG2a, κ - Reactivity Hu - 100 Tests
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Klon
    P282
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product CD59 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Probenmenge
    20 μL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
  • Davies, Lachmann: "Membrane defence against complement lysis: the structure and biological properties of CD59." in: Immunologic research, Vol. 12, Issue 3, pp. 258-75, (1994) (PubMed).

    Deckert, Kubar, Bernard: "CD58 and CD59 molecules exhibit potentializing effects in T cell adhesion and activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 3, pp. 672-7, (1992) (PubMed).

    Deckert, Kubar, Zoccola, Bernard-Pomier, Angelisova, Horejsi, Bernard: "CD59 molecule: a second ligand for CD2 in T cell adhesion." in: European journal of immunology, Vol. 22, Issue 11, pp. 2943-7, (1992) (PubMed).

    Guesdon, Ternynck, Avrameas: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).

  • Target
    CD59
    Andere Bezeichnung
    CD59 (CD59 Produkte)
    Synonyme
    16.3A5 antikoerper, 1F5 antikoerper, EJ16 antikoerper, EJ30 antikoerper, EL32 antikoerper, G344 antikoerper, HRF-20 antikoerper, HRF20 antikoerper, MAC-IP antikoerper, MACIF antikoerper, MEM43 antikoerper, MIC11 antikoerper, MIN1 antikoerper, MIN2 antikoerper, MIN3 antikoerper, MIRL antikoerper, MSK21 antikoerper, p18-20 antikoerper, Cd59a antikoerper, Cd59b antikoerper, MACIP antikoerper, CD59 molecule (CD59 blood group) antikoerper, CD59 molecule antikoerper, CD59 antikoerper, Cd59 antikoerper
    Pathways
    Komplementsystem
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